1071-49-4Relevant academic research and scientific papers
A rapid reaction releasing the carboxyl terminal residues of peptides
Yagisawa, Shiroki,Urakami, Masako
, p. 7557 - 7560 (2007/10/03)
Alcoholysis of peptide oxazolones in alcohols containing dilute acid, such as 0.02M HCl, gives the C-terminal amino acid and the ester of the shortened peptide within 10 minutes at room temperature in 30-70% yields. This together with the finding that the peptide oxazolones can be formed within 3 minutes with alkylchloroformates enables the rapid removal of peptide C-terminal residues.
N-METHOXYDIACETAMIDE: A NEW SELECTIVE ACETYLATING AGENT
Kikugawa, Yasuo,Mitsui, Kimiyo,Sakamoto, Takeshi,Kawase, Masami,Tamiya, Hiroshi
, p. 243 - 246 (2007/10/02)
A simple and efficient method for the direct chemoselective acetylation of primary amines in the presence of alcohols or secondary amines using a new reagent N-methoxydiacetamide is described.
