1071216-81-3

Basic information

• Product Name: 3-(1-Benzyl-pyrrolidin-3-ylamino)-4-(2,2-dimethoxy-ethyl)-benzoic acid methyl ester
• Synonyms: 3-(1-Benzyl-pyrrolidin-3-ylamino)-4-(2,2-dimethoxy-ethyl)-benzoic acid methyl ester
• CAS NO: 1071216-81-3
• Molecular Weight: 398.502
• Mol File: 1071216-81-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-(1-Benzyl-pyrrolidin-3-ylamino)-4-(2,2-dimethoxy-ethyl)-benzoic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(1-Benzyl-pyrrolidin-3-ylamino)-4-(2,2-dimethoxy-ethyl)-benzoic acid methyl ester(1071216-81-3)
• EPA Substance Registry System: 3-(1-Benzyl-pyrrolidin-3-ylamino)-4-(2,2-dimethoxy-ethyl)-benzoic acid methyl ester(1071216-81-3)

Safety Data

• Hazardous Substances Data: 1071216-81-3(Hazardous Substances Data)

Upstream product

• 146667-95-0 2,2-dimethoxy-1-(4-methoxycarbonyl-2-nitrophenyl)ethane 
• 96-98-0 4-methyl-3-nitrobenzoic acid 
• 775-16-6 N-benzyl-3-pyrrolidinone 
• 167478-76-4 2-amino-4-carbomethoxy-phenylacetaldehyde dimethylacetal 

Relevant articles and documents

Convenient preparation of N-substituted indoles by modified Leimgruber-Batcho indole synthesis

A modified reductive alkylation of pre-indole 3, prepared from readily available Leimgruber-Batcho indole synthesis derived intermediates, followed by acidic methanolysis generates 6-carbomethoxy-N-substituted indoles. The three step preparation of pre-indole 3 from substituted 2-nitrotoluene 1 in 66% yield and conversion to a variety of N-substituted indoles is presented.