107150-74-3Relevant articles and documents
Copper-Catalyzed Ullmann-Type Coupling and Decarboxylation Cascade of Arylhalides with Malonates to Access α-Aryl Esters
Cheng, Fei,Chen, Tao,Huang, Yin-Qiu,Li, Jia-Wei,Zhou, Chen,Xiao, Xiao,Chen, Fen-Er
supporting information, p. 115 - 120 (2022/01/04)
We have developed a high-efficiency and practical Cu-catalyzed cross-coupling to directly construct versatile α-aryl-esters by utilizing readily available aryl bromides (or chlorides) and malonates. These gram-scale approaches occur with turnovers of up to 1560 and are smoothly conducted by the usage of a low catalyst loading, a new available ligand, and a green solvent. A variety of functional groups are tolerated, and the application occurs with α-aryl-esters to access nonsteroidal anti-inflammatory drugs (NSAIDs) on the gram scale.
Synthesis and hypolipidemic activity of novel 4-oxo- and 4-thioxo-4H-benzopyran-2-phenylalkanoic acids and esters
Orjales, A.,Berisa, A.,Alonso-Cires, L.
, p. 27 - 31 (2007/10/02)
Novel 4-oxo- and 4-thioxo-4H-benzopyran-2-phenylalkanoic acids and esters have been prepared and evaluated for their hypolipidemic activity.Among these compounds 3'-alkanoyl derivatives show superior activity, decreasing total cholesterol, triglycerides a