107150-74-3

Upstream product

• 64-17-5 ethanol 
• 2084-13-1 3-carboxymethyl-benzoic acid 
• 16532-78-8 3-(cyanomethyl)benzonitrile 
• 54589-54-7 ethyl 3-(chloromethyl)benzoate 
• 541-41-3 chloroformic acid ethyl ester 
• 24398-88-7 ethyl 3-bromobenzoate 
• 105-53-3 diethyl malonate 

Downstream Products

• 155938-67-3 3-carboethoxymethylbenzoyl chloride 
• 155938-40-2 3'-carboxymethylflavone methyl ester 
• 155938-69-5 3'-carboxymethylflavone ethyl ester 
• 155938-42-4 [3-(4-Oxo-4H-chromen-2-yl)-phenyl]-acetic acid isopropyl ester 
• 155938-41-3 [3-(4-Oxo-4H-chromen-2-yl)-phenyl]-acetic acid propyl ester 
• 155938-44-6 [3-(4-Oxo-4H-chromen-2-yl)-phenyl]-acetic acid isobutyl ester 
• 155938-43-5 [3-(4-Oxo-4H-chromen-2-yl)-phenyl]-acetic acid butyl ester 
• 155938-25-3 [3-(6-Methyl-4-oxo-4H-chromen-2-yl)-phenyl]-acetic acid ethyl ester 
• 155938-29-7 [3-(5,7-Dimethyl-4-oxo-4H-chromen-2-yl)-phenyl]-acetic acid ethyl ester 
• 155938-45-7 [3-(4-Oxo-4H-chromen-2-yl)-phenyl]-acetic acid octyl ester 
• 155938-46-8 [3-(4-Oxo-4H-chromen-2-yl)-phenyl]-acetic acid hexadecyl ester 

Relevant academic research and scientific papers

Copper-Catalyzed Ullmann-Type Coupling and Decarboxylation Cascade of Arylhalides with Malonates to Access α-Aryl Esters

We have developed a high-efficiency and practical Cu-catalyzed cross-coupling to directly construct versatile α-aryl-esters by utilizing readily available aryl bromides (or chlorides) and malonates. These gram-scale approaches occur with turnovers of up to 1560 and are smoothly conducted by the usage of a low catalyst loading, a new available ligand, and a green solvent. A variety of functional groups are tolerated, and the application occurs with α-aryl-esters to access nonsteroidal anti-inflammatory drugs (NSAIDs) on the gram scale.

Large-scale preparation of polyfunctional benzylic zinc reagents by direct insertion of zinc dust into benzylic chlorides in the presence of lithium chloride

Highly functionalized benzylic zinc chlorides are prepared by the direct insertion of commercially available zinc dust into the corresponding benzylic chlorides in the presence of stoichiometric amount of lithium chloride. These polyfunctional zinc organometallics react with various electrophiles leading to a broad range of functionalized products. Georg Thieme Verlag Stuttgart.

Synthesis and hypolipidemic activity of novel 4-oxo- and 4-thioxo-4H-benzopyran-2-phenylalkanoic acids and esters

Novel 4-oxo- and 4-thioxo-4H-benzopyran-2-phenylalkanoic acids and esters have been prepared and evaluated for their hypolipidemic activity.Among these compounds 3'-alkanoyl derivatives show superior activity, decreasing total cholesterol, triglycerides a