107165-67-3

Basic information

• Product Name: Benzoxazole,4-Methyl-
• Synonyms: Benzoxazole,4-Methyl-;4-Methylbenzoxazole;4-Methyl-1,3-benzoxazole;4-Methylbenzo[d]oxazole
• CAS NO: 107165-67-3
• Molecular Formula: C8H7NO
• Molecular Weight: 133.14728
• Mol File: 107165-67-3.mol
• Article Data: 13

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Benzoxazole,4-Methyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzoxazole,4-Methyl-(107165-67-3)
• EPA Substance Registry System: Benzoxazole,4-Methyl-(107165-67-3)

Safety Data

• Hazardous Substances Data: 107165-67-3(Hazardous Substances Data)

Usage

General Description

4-Methylbenzoxazole is a chemical compound with the molecular formula C9H9NO. It is a heterocyclic aromatic compound that contains a benzene ring fused to an oxazole ring. 4-Methylbenzoxazole is used as a building block in the synthesis of pharmaceuticals and agrochemicals, as well as in the production of dyes and pigments. It is also used as a fragrance ingredient in perfumes and other personal care products. Additionally, 4-Methylbenzoxazole has been studied for its potential anti-cancer and anti-inflammatory properties. This chemical is considered to be relatively safe, but it should be handled and stored with appropriate safety precautions.

Upstream product

• 2835-97-4 2-amino-3-methylphenol 
• 20353-93-9 [3-(dimethylamino)-2-azaprop-2-en-1-ylidene]-dimethylammonium chloride 
• 122-51-0 orthoformic acid triethyl ester 
• 56-40-6 glycine 
• 488-17-5 3-methylbenzene-1,2-diol 
• 74-89-5 methylamine 
• 149-73-5 trimethyl orthoformate 

Downstream Products

• 685889-92-3 4-methyl-2-(p-tolyl)benzo[d]oxazole 
• 77791-11-8 4-methyl-2-phenyl-1,3-benzoxazole 
• 1582789-78-3 (E)-4-methyl-2-styrylbenzo[d]oxazole 
• 1422200-33-6 4-methyl-2-(2,3,4,5-tetrafluoro-6-(pyridin-2-yl)phenyl)benzoxazole 

Relevant articles and documents

TETRAHYDROISOQUINOLINE DERIVATIVE, PREPARATION METHOD THEREFOR AND USE THEREOF

Provided are a tetrahydroisoquinoline derivative, a preparation method therefor and an application thereof in medicine. In particular, provided are a tetrahydroisoquinoline derivative represented by general formula (I), a preparation method therefor and a

COMPOUND HAVING ZNF143 INHIBITORY ACTIVITY AND USE THEREOF

PROBLEM TO BE SOLVED: To provide a compound having a ZNF143 inhibitory activity as well as to provide a ZNF143 inhibitory agent and pharmaceutical composition containing the same. SOLUTION: Provided is a compound represented by formula (I) or a salt thereof as well as a ZNF143 inhibitory agent containing the same and a pharmaceutical composition having the same as an active ingredient. A-B-C-D (I)[A is H, a methyl group, a naphthyl group, a phenyl group or a nitrogen-containing heterocyclic ring; B is as shown below, and C is an amide bond or a heteroaromatic ring containing N and O; D is a substituted/unsubstituted phenyl group or a monocyclic heteroaromatic ring containing N or S; and C and D are both fused heterocyclic ring or the like optionally having a substituent group.]. SELECTED DRAWING: Figure 1 COPYRIGHT: (C)2016,JPOandINPIT

Direct C-H iodination of 1,3-azoles catalysed by CuBr2

A mild method was developed for the direct C-H iodination of 1,3-azoles catalysed by CuBr2. Compared with the traditional metalation/iodination sequences carried out with nBuLi or TMPLi (TMP = 2,2,6,6-tetramethylpiperidino), a relatively weaker base, LiOtBu, was used in the presence of 1,10-phenanthroline. Five series of 1,3-azoles, including benzoxazole, benzothiozole, N-methyl-benzoimidazole, 5-phenyloxazole and 2-phenyl-1,3,4-oxadiazole were tested and afforded the corresponding iodination products.