107165-82-2

Upstream product

• 41467-26-9 1-(4-chlorophenyl)-3,3-bis(methylsulfanyl)-2-propen-1-one 
• 107-15-3 ethylenediamine 
• 50850-04-9 1-(4-chlorophenyl)-3,3-dimercapto-2-propen-1-one 
• 4640-66-8 p-chlorobenzoylacetonitrile 
• 81471-33-2 3-(4-Chlorphenyl)-3-oxo-propionimidsauere-ethylester-hydrochlorid 

Downstream Products

• 132111-57-0 3-(p-chlorobenzoyl)-5,6-dihydro-4H-imidazo-<1,2-c><1,2,3>triazole 
• 132111-53-6 1-(p-methoxyphenyl)-4-(2-imidazolinyl)-5-(p-chlorophenyl)-1,2,3-triazole 
• 1146216-93-4 C₁₉H₁₀Cl₄N₄O 
• 1146216-95-6 C₁₉H₁₀ClF₃N₄O 
• 102121-98-2 4-amino-2,5,6-trifluoroisophthalonitrile 
• 1258511-61-3 (4-chlorophenyl)(2,3-dihydro-7-hydroxy-5,6-dimethoxy-8-methyl-1H-imidazo[1,2-a]indol-9-yl)methanone 
• 1327166-78-8 6-(4-chlorophenyl)-8,9-dihydro-7-azapyrrolizino[1,2-c]quinolin-11-one 
• 1327166-83-5 2-chloro-6-(4-chlorophenyl)-8,9-dihydro-7-azapyrrolizino[1,2-c]quinolin-11-one 
• 1463517-83-0 (4Z)-4-(3-(4-chlorophenyl)-2-(imidazolidin-2-ylidene)-3-oxopropylidene)-3-methyl-1-phenyl-1H-pyrazol-5(4H)-one 
• 1463517-94-3 (4Z)-4-(3-(4-chlorophenyl)-2-(imidazolidin-2-ylidene)-3-oxopropylidene)-1-phenyl-3-(trifluoromethyl)-1H-pyrazol-5(4H)-one 

Relevant academic research and scientific papers

Synthesis of Partially Reduced Imidazo[1,2- a ]pyridines through an Unprecedented Base-Mediated (4+2) Cyclization

A water-mediated regioselective synthesis of 6,7-diaryl-5-oxo-2,3,5,6-tetrahydroimidazo[1,2-a]pyridine-6-carbonitriles was performed by the reaction of 2-[1-cyano-2,2-bis(methylsulfanyl)vinyl]benzonitrile with 1-aryl-2-(imidazolidin-2-ylidene)ethanones un

Three-component synthesis of indanone-fused spirooxindole derivatives

A simple, straightforward and versatile multicomponent protocol for the synthesis of indanone-fused spirooxindole derivatives has been developed. The strategy involves the one-pot three-component reaction of heterocyclic ketene aminals, 1H-indene-1,3(2H)-

The synthesis of fluoroheterocyclic ketene aminals

The synthesis of fluoroheterocyclic ketene aminals was investigated. Fluorobenzyl ketene dithioacetals 1c reacted with nitric acid in the presence of concentrated sulfuric acid to give compound 2c. 1 reacted with diamines to afford 3-4. C-fluorobenzylatio

Multicomponent Cascade Reaction by Metal-Free Aerobic Oxidation for Synthesis of Highly Functionalized 2-Amino-4-coumarinyl-5-arylpyrroles

A novel approach has been constructed for the synthesis of two types of 2-amino-4-coumarinyl-5-arylpyrroles (ACAPs, 5 and 6) through a cascade reaction and a metal-free catalyzed aerobic oxidation reaction of arylglyoxal monohydrates 1, 1,1-enediamines (E

Multicomponent Tether Catalysis Synthesis of Highly Functionalized 4-(Pyridin-2-ylmethyl)-2-aminopyrroles via Cascade Reaction Is Accompanied by Decarboxylation

A multicomponent tether catalysis protocol for the synthesis of 4-(pyridin-2-ylmethyl)-2-aminopyrroles (PMAPs) was constructed by simply refluxing a mixture of ethyl 2-(pyridin-2-yl)acetates 1 and various types of arylglyoxal monohydrates 2 and different heterocyclic ketene aminals 3 in EtOH solvent. Based on this reaction, a series of highly functionalized PMAPs were obtained through a novel cascade reaction accompanied by a decarboxylation mechanism. As a result, the pyridin-2-ylmethyl was successfully introduced in the target compounds, and a library of PMAPs were easily constructed using the cascade reaction described in this study. This protocol demonstrated that the most important feature was the decarboxylation reaction of the 2-(pyridin-2-yl)acetates 1, which can be used in the synthesis of pyridin-2-ylmethyl-substituted heterocycles, including pyrroles, pyridines, quinolones, and other heterocyclic compounds resembling those found in nature.

Synthesis of imidazo[1,2-a]pyridines and pyrido[1,2-a]pyrimidines in water and their snar cyclizations

Synthesis of tetrahydroimidazo[1,2-a]pyridines and tetrahydropyrido[1,2-a] pyrimidines by a one-pot and three component reaction of α-oxoketenedithioacetals, diamines and DMAD in water has been described. Different routes for accessing the desired compoun

Synthesis of annelated [a]aza-anthracenones and thieno[3,2-g]aza- naphthalenones through ring transformation of 2H-pyran-2-one followed by photocyclization

A concise synthesis of some new classes of heterocycles (4-aryl-11-oxo-1,2,3,11-tetrahydro-1,3a-diaza-cyclopenta[a]anthracen-6- carbonitriles and 5-aryl-12-oxo-1,3,4,12-tetrahydro-2H-1,4a-diazabenzo[a] anthracene-7-carbonitriles) has been developed by the

SYNTHESIS OF BENZOYL SUBSTITUTED HETEROCYCLIC KETENE AMINALS BY CONDENSATION OF BENZOYL KETENE MERCAPTALS WITH DIAMINES

2-(Benzoylmethylene)imidazolidines 2 and 5, -hexahydropyrimidines 3 and 6, or -hexahydro-1H-1,3-diazepines 4 were synthesized by the reaction of benzoyl substituted ketene mercaptals 1 with diamines.

Synthesis of 2-(Benzoylmethylene)imidazolidines and -hexahydropyrimidines by Condensation of Ethyl Benzoylacetimidates With 1,2-Ethanediamine or 1,3-Propanediamine, and Some Addition Reactions

Ethyl benzoylacetimidates react with 1,2-ethanediamine or 1,3-propanediamine in absolute ethanol to afford the 2-(benzoylmethylene)imidazolidines or -hexahydropyrimidines, respectively.The structure of these products as ketene aminals is confirmed by spec