1072145-53-9

Basic information

• Product Name: 2',7-(dibenzyloxy)-4'-(methoxymethyloxy)isoflav-3-ene
• Synonyms: 2',7-(dibenzyloxy)-4'-(methoxymethyloxy)isoflav-3-ene
• CAS NO: 1072145-53-9
• Molecular Weight: 480.56
• Mol File: 1072145-53-9.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 2',7-(dibenzyloxy)-4'-(methoxymethyloxy)isoflav-3-ene(CAS DataBase Reference)
• NIST Chemistry Reference: 2',7-(dibenzyloxy)-4'-(methoxymethyloxy)isoflav-3-ene(1072145-53-9)
• EPA Substance Registry System: 2',7-(dibenzyloxy)-4'-(methoxymethyloxy)isoflav-3-ene(1072145-53-9)

Safety Data

• Hazardous Substances Data: 1072145-53-9(Hazardous Substances Data)

Upstream product

• 70120-18-2 3-(benzyloxy)-4-bromophenol 
• 6626-15-9 4-Bromoresorcinol 
• 3769-41-3 3-Benzyloxyphenol 
• 1575479-23-0 C₁₅H₁₇BO₅ 
• 1575479-05-8 C₁₆H₁₃ClO₂ 
• 1072145-51-7 1-(2'-benzyloxy-4'-methoxymethylenoxy)phenyl-2-iodoethanone 
• 1026107-41-4 2-benzyloxy-4-methoxymethylenoxyacetophenone 
• 412339-25-4 4-benzyloxy-salicylalcohol 
• 89-84-9 2',4'-dihydroxy-4-acetophenone 
• 65490-08-6 2-hydroxy-4-(methoxymethoxy)acetophenone 
• 52085-14-0 4-benzoxy-salicylaldehyde 
• 100-39-0 benzyl bromide 
• 95-01-2 2,4-Dihydroxybenzaldehyde 
• 1072145-52-8 2-(5'-benzyloxy-2'-hydroxymethyl)phenoxy-1-(2'-benzyloxy-4'-methoxy-methylenoxy)phenylethanone 

Downstream Products

• 1072145-56-2 2',7-dibenzyloxy-4'-hydroxy-isoflav-3-ene 
• 57103-57-8 (+/-)-glyceollin I 
• 1072145-54-0 2',7-dibenzyloxy-4'-(tert-butyldimethylsilyloxy)isoflav-3-ene 
• 1072145-55-1 (+)-4'-tert-butyldimethylsilyloxy-2',7-(dibenzyloxy)isoflavan-3,4-diol 
• 57103-57-8 (+)-Glyceollin I 

Relevant articles and documents

Formal synthesis of soybean phytoalexin glyceollin i

Glyceollins are well-known phytoalexins isolated from soybean (Glycine max). An efficient three-step synthesis was developed for the preparation of the key intermediate in Khupse's glyceollin I synthesis. Claisen rearrangement-cyclization cascade reaction

Multigram synthesis of glyceollin i

Scaled-up procedures and preparation of glyceollin I in multigram quantities are described. The synthesis features construction of a cis-fused ring system in high enantiomeric excess after Sharpless asymmetric dihydroxylation of a key intermediate that is initially produced by an intramolecular Wittig reaction to afford the requisite alkene while simultaneously forming the first ring. The overall yield is 12% after 11 steps.

Total syntheses of racemic, natural (-) and unnatural (+) glyceollin I

(Chemical Equation Presented) The first total syntheses of racemic glyceollin I and its enantiomers are described. A Wittig approach was utilized as an entry to the appropriately substituted isoflav-3-ene so that an osmium tetroxide mediated asymmetric dihydroxylation could be deployed for stereospecific Introduction of the 6a-hydroxy group. While using triphenylphosphine hydrobromide, a novel method was found for gently removing MOM from protected phenolic hydroxyl groups present within sensitive systems.