107288-98-2

Basic information

• Product Name: 4-phenyl-2-(trifluoromethyl)quinazoline
• Synonyms: 4-phenyl-2-(trifluoromethyl)quinazoline
• CAS NO: 107288-98-2
• Molecular Weight: 274.245
• Mol File: 107288-98-2.mol

Chemical Properties

• CAS DataBase Reference: 4-phenyl-2-(trifluoromethyl)quinazoline(CAS DataBase Reference)
• NIST Chemistry Reference: 4-phenyl-2-(trifluoromethyl)quinazoline(107288-98-2)
• EPA Substance Registry System: 4-phenyl-2-(trifluoromethyl)quinazoline(107288-98-2)

Safety Data

• Hazardous Substances Data: 107288-98-2(Hazardous Substances Data)

Upstream product

• 407-25-0 trifluoroacetic anhydride 
• 1885-29-6 anthranilic acid nitrile 
• 64718-13-4 N-(2-Cyanophenyl)-2,2,2-trifluoroacetamide 
• 98-80-6 phenylboronic acid 

Relevant articles and documents

Pd-Catalyzed tandem reaction of N-(2-cyanoaryl)benzamides with arylboronic acids: synthesis of quinazolines

The synthesis of 2,4-disubstituted quinazolines by a palladium-catalyzed reaction of arylboronic acids with N-(2-cyanoaryl)benzamides has been developed with moderate to excellent yields. The method shows good functional group tolerance. In particular, ha

SYNTHESIS OF QUINAZOLINES

Grignard reagents reacted with 2-aminobenzonitrile to give the intermediate (10), which readily could be cyclized to quinazolines by reaction with carbonyl compounds (e.g. acid chlorides, anhydrides, formates and oxalates).The intermediate (10) and aldehy