1073-65-0

Usage

Uses

Used in Pharmaceutical Industry:
4-Pyrimidinecarboxaldehyde, oxime (7CI,8CI,9CI) is used as a key intermediate in the synthesis of various pharmaceutical compounds. Its unique structure allows it to be incorporated into the development of new drugs, potentially leading to the discovery of novel therapeutic agents.
Used in Agrochemical Industry:
In the agrochemical industry, 4-Pyrimidinecarboxaldehyde, oxime (7CI,8CI,9CI) serves as a building block for the creation of new agrochemicals. Its properties make it suitable for the synthesis of compounds with potential applications in crop protection, pest control, and other agricultural areas.
Used in Material Science:
4-Pyrimidinecarboxaldehyde, oxime (7CI,8CI,9CI) is utilized in the field of material science for the development of new materials with unique properties. Its structure and reactivity contribute to the synthesis of advanced materials with potential applications in various industries, such as electronics, energy, and nanotechnology.
Used in Organic Synthesis:
As a versatile reagent in organic synthesis, 4-Pyrimidinecarboxaldehyde, oxime (7CI,8CI,9CI) is employed in various chemical reactions to form a wide range of organic compounds. Its aldehyde and oxime functionalities enable it to participate in numerous synthetic pathways, making it a valuable tool for chemists in the development of new organic molecules.

InChI:InChI=1/C5H5N3O/c9-8-3-5-1-2-6-4-7-5/h1-4H,(H,6,7)/b5-3-

Upstream product

• 3438-46-8 4-Methylpyrimidine 

Downstream Products

• 42839-04-3 Pyrimidine-4-carbonitrile 
• 39870-05-8 4-acetyl pyrimidine 
• 618446-08-5 C-pyrimidin-4-yl-methylamine dihydrogen chloride 

Relevant academic research and scientific papers

SUBSTITUTED ARYL-AMINE DERIVATIVES AND METHODS OF USE

The present invention provides classes of compounds, including-their pharmaceutically acceptable derivatives, useful for treating angiogenesis and related diseases such as cancer. Formula I and II wherein R is a 9- or 10-membered heterocyclyl ring selected from 7-isoquinolinyl,..2-methyl-3-oxo-2,3-dihydroindazol-6-yl, [1,6]-naphthydrin-3-yl, [1,7]-naphthydrin-2-yl, 1-oxo-2,3-dihydrobenzofuran-4-yl, 3-oxo-2,3-dihydrobenzofuran-5-yl, dihydro-benzodioxinyl, 6-quinazolinyl, 2-amino-6-quinazolinyl, 4-methylamino-6-quinazolinyl, 2,4-diamino-6 quinazolinyl, 3-oxo-3,4-dihydro-1,4-benzoxazin-6-yl, 2,2-difluoro-l;3-benzodioxol-5-yl and 2,2,3,3 tetrafluoro-2,3-dihydro-l,4-benzodioxin-6-yl, each of which is optionally substituted with one or more substituents selected from halo, haloakyl, C1-6 alkyl, C2-8 alkenyl, C2-8 alkynyl, N-dimethylamino-C1-6-alkyl, N-dimethylamino-C1-6-alkoxy, amino, alkyl-carbonylamino, morpholino-sulfonyl, amino-sulfonyl, oxazolyl, pyrrolyl,4 morpholinyl, carboxyl, cyano, and acetyl; wherein R1 in formula I is selected from unsubstituted or substituted phenyl, 5-6 membered heteroaryl, 9-10 membered bicyclic heterocyclyl and 11-14 membered tricyclic heterocyclyl, and R1 in formula II is selected from specific bicyclic heterocycles.

Substituted alkylamine derivatives and methods of use

Selected amines are effective for prophylaxis and treatment of diseases, such as angiogenesis mediated diseases. The invention encompasses novel compounds, analogs, prodrugs and pharmaceutically acceptable salts thereof, pharmaceutical compositions and methods for prophylaxis and treatment of diseases and other maladies or conditions involving, cancer and the like. The subject invention also relates to processes for making such compounds as well as to intermediates useful in such processes.