1073143-37-9Relevant articles and documents
ROR GAMMA AGONISTS AS ENHANCERS OF PROTECTIVE IMMUNITY
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Page/Page column 16; 17; 19, (2017/05/19)
The T cell specific RORgamma isoform RORgammat has been shown to be the key lineage-defining transcription factor to initiate the differentiation program of TH17 and TC17 cells, cells that have demonstrated anti-tumor efficacy, RORga
LXR antagonists with a 5-substituted phenanthridin-6-one skeleton: Synthesis and LXR transrepression activities of conformationally restricted carba-T0901317 analogs
Aoyama, Atsushi,Aoyama, Hiroshi,Dodo, Kosuke,Makishima, Makoto,Hashimoto, Yuichi,Miyachi, Hiroyuki
body text, p. 137 - 142 (2011/03/22)
Conformationally restricted heterocyclic analogs of carba-T0901317, a liver X receptor (LXR) antagonist, were prepared via the palladium catalized cyclization reaction as a key step. In vitro transactivation assay revealed that the structural modification