1073143-41-5Relevant articles and documents
LXR antagonists with a 5-substituted phenanthridin-6-one skeleton: Synthesis and LXR transrepression activities of conformationally restricted carba-T0901317 analogs
Aoyama, Atsushi,Aoyama, Hiroshi,Dodo, Kosuke,Makishima, Makoto,Hashimoto, Yuichi,Miyachi, Hiroyuki
, p. 137 - 142 (2011/03/22)
Conformationally restricted heterocyclic analogs of carba-T0901317, a liver X receptor (LXR) antagonist, were prepared via the palladium catalized cyclization reaction as a key step. In vitro transactivation assay revealed that the structural modification