1073149-00-4 Usage
Uses
Used in Pharmaceutical Industry:
(S)-1-(5-fluoropyridin-2-yl)ethanamine hydrochloride serves as a key intermediate in the synthesis of various pharmaceuticals, leveraging its unique chemical properties to contribute to the development of novel drugs. The presence of the fluorine atom can modulate the pharmacokinetics and pharmacodynamics of the resulting compounds, potentially improving their efficacy and safety profiles.
Used in Organic Synthesis:
In the field of organic synthesis, (S)-1-(5-fluoropyridin-2-yl)ethanamine hydrochloride is utilized as a versatile building block for the creation of a range of organic compounds. Its reactivity and structural features make it suitable for use in the synthesis of complex organic molecules, including those with potential applications in materials science, agrochemicals, and specialty chemicals.
Used in Research and Development:
(S)-1-(5-fluoropyridin-2-yl)ethanamine hydrochloride is employed in research and development settings to explore its potential applications and to understand its chemical behavior. (S)-1-(5-fluoropyridin-2-yl)ethanaMine hydrochloride's unique properties make it an interesting subject for studies aimed at discovering new reactions, mechanisms, and applications in various chemical and biological contexts.
Used in Drug Development:
As a component in drug development, (S)-1-(5-fluoropyridin-2-yl)ethanamine hydrochloride is used to construct new molecular entities with potential therapeutic applications. Its specific stereochemistry and the presence of the fluorine atom can influence the binding affinity, selectivity, and overall performance of the resulting drug candidates, making it a valuable tool in the quest for new medicines.
Check Digit Verification of cas no
The CAS Registry Mumber 1073149-00-4 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,7,3,1,4 and 9 respectively; the second part has 2 digits, 0 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 1073149-00:
(9*1)+(8*0)+(7*7)+(6*3)+(5*1)+(4*4)+(3*9)+(2*0)+(1*0)=124
124 % 10 = 4
So 1073149-00-4 is a valid CAS Registry Number.
1073149-00-4Relevant academic research and scientific papers
Discovery of pyrazol-3-ylamino pyrazines as novel JAK2 inhibitors
Ioannidis, Stephanos,Lamb, Michelle L.,Davies, Audrey M.,Almeida, Lynsie,Su, Mei,Bebernitz, Geraldine,Ye, Minwei,Bell, Kirsten,Alimzhanov, Marat,Zinda, Michael
scheme or table, p. 6524 - 6528 (2010/05/18)
The design, synthesis and biological evaluation of a series of pyrazol-3-ylamino pyrazines as potent and selective JAK2 kinase inhibitors is reported, along with the pharmacokinetic and pharmacodynamic properties of lead compounds.
CHEMICAL COMPOUNDS 000-1
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Page/Page column 55-56, (2009/04/25)
The present invention relates to compounds of Formula (I) and to their salts, pharmaceutical compositions, methods of use, and methods for their preparation. These compounds provide a treatment for myeloproliferative disorders and cancer.
9- (PYRAZOL- 3 -YL) - 9H- PURINE-2 -AMINE AND 3- (PYRAZ0L-3-YL) -3H-IMIDAZ0 [4, 5-B] PYRIDIN-5-AMINE DERIVATIVES AND THEIR USE FOR THE TREATMENT OF CANCER
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Page/Page column 52, (2009/01/20)
The present invention relates to compounds of Formula (I): and to their pharmaceutical compositions, and to their methods of use. These compounds provide a treatment for myeloproliferative disorders and cancer.
5-AMINOPYRAZOL-3-YL-3H-IMIDAZO [4,5-B] PYRIDINE DERIVATIVES AND THEIR USE FOR THE TREATMENT OF CANCER
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, (2008/12/08)
The present invention relates to compounds of Formula (I) and to their pharmaceutical compositions, and to their methods of use. These novel compounds provide a treatment for myeloproliferative disorders and cancer.
