1073353-89-5

Basic information

• Product Name: 2-(2-Fluoro-4-nitrophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
• Synonyms: 2-(2-Fluoro-4-nitrophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane;2-Fluoro-4-nitrophenylboronic acid, pinacol ester;2-Fluoro-4-nitrobenzeneboronic acid pinacol ester, 96%
• CAS NO: 1073353-89-5
• Molecular Formula: C₁₂H₁₅BFNO₄
• Molecular Weight: 267.0612032
• Mol File: 1073353-89-5.mol
• Article Data: 6

Chemical Properties

• Appearance: /Solid
• CAS DataBase Reference: 2-(2-Fluoro-4-nitrophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(2-Fluoro-4-nitrophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane(1073353-89-5)
• EPA Substance Registry System: 2-(2-Fluoro-4-nitrophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane(1073353-89-5)

Safety Data

• Hazardous Substances Data: 1073353-89-5(Hazardous Substances Data)

Usage

Uses

2-Fluoro-4-nitrophenylboronic acid, pinacol ester

Upstream product

• 369-35-7 2-fluoro-4-nitroaniline 
• 73183-34-3 bis(pinacol)diborane 
• 2996-30-7 2-fluoro-1-iodo-4-nitrobenzene 
• 185331-69-5 1-bromo-2-fluoro-4-nitrobenzene 

Downstream Products

• 1413921-01-3 2-(2-fluoro-4-nitrophenyl)-5-(2-isopropoxy-4-nitrophenyl)furan 
• 1413921-05-7 C₁₉H₁₉FN₂O₂ 
• 1413921-10-4 C₃₁H₂₇FN₆O₂ 
• 819057-45-9 3-fluoro-4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-phenylamine 
• 1565857-74-0 (3-fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)trimethylstannane 
• 1228778-59-3 2-iodotriphenylene 
• 1597602-19-1 2-(2-fluoro-4-nitrophenyl)-5-nitrobenzophenone 
• 1597602-38-4 C₂₅H₂₄FN₃O₄ 
• 1597602-59-9 3,8-dinitro-5-(hex-1’-yl)-6-phenylphenanthridinium chloride 

Relevant articles and documents

Intramolecular aryl-aryl coupling: Via C-F bond activation tolerant towards C-I functionality

Herein we report a transition-metal free activation of a particularly stable aromatic carbon-fluorine bond allowing intramolecular aryl-aryl coupling which is orthogonal to carbon-iodine functionality.

HETEROCYCLIC COMPOUNDS AS PI3K-y INHIBITORS

This application relates to compounds of Formula (I): or pharmaceutically acceptable salts or stereoisomers thereof, which are inhibitors of PI3K-γ which are useful for the treatment of disorders such as autoimmune diseases, cancer, cardiovascular diseases, and neurodegenerative diseases.

Synthesis of trimethylstannyl arylboronate compounds by sandmeyer-type transformations and their applications in chemoselective cross-coupling reactions

A synthetic method based on Sandmeyer-type reactions to access both tin- and boron-substituted arenes from nitroaniline derivatives is described. This transformation can be applied to the synthesis of a series of functionalized trimethylstannyl arylboronates. In addition, the chemoselective reaction of the Stille and Suzuki-Miyaura cross-coupling reactions is explored, and a series of m- and p-terphenyl derivatives have been synthesized by conducting consecutive one-pot Stille and Suzuki-Miyaura cross-coupling reactions.