107355-76-0Relevant academic research and scientific papers
Conformationally restricted analogues of disoxaril: A comparison of the activity against human rhinovirus types 14 and 1A
Mallamo,Diana,Pevear,Dutko,Chapman,Kim,Minor,Oliveira,Rossmann
, p. 4690 - 4695 (2007/10/02)
A series of conformationally restricted analogs of disoxaril has been synthesized and evaluated against human rhinovirus types (HRV) 14 and 1A. The sensitivity of these serotypes to this series varied and was dependent upon the length of the molecule as w
Di-heterocyclic compounds and their use as antiviral agents
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, (2008/06/13)
Compounds of the formulas: STR1 wherein Het is an oxazole or oxazine moiety; X is O, S or SO, n is an integer from 3 to 9, Y is an aliphatic bridge; and the various R groups represent hydrogen or various substituents as described herein, are useful as antiviral agents, especially against picornaviruses. N-(Chloroalkyl)amide intermediates for the compounds of Formula I are also active as antiviral agents. Related compounds outside the scope of the above formulas are also disclosed.
