107377-07-1 Usage
Description
4-N-BUTYLBENZAMIDE, with the molecular formula C11H15NO, is a chemical compound that is a derivative of benzamide. It features a butyl group attached to the nitrogen atom, which distinguishes it from other benzamide derivatives. 4-N-BUTYLBENZAMIDE is known for its white to off-white crystalline solid form at room temperature and is widely utilized in research and industrial applications, particularly as a building block for synthesizing other organic compounds. Additionally, it has garnered interest for its potential pharmaceutical properties, such as its ability to interact with receptors in the central nervous system.
Uses
Used in Research and Industrial Applications:
4-N-BUTYLBENZAMIDE is used as a building block for the synthesis of other organic compounds, serving as a key intermediate in the creation of various chemical entities. Its structural features make it a versatile component in the development of new molecules with specific functions and properties.
Used in Pharmaceutical Research:
4-N-BUTYLBENZAMIDE is used as a compound of interest in pharmaceutical research due to its potential to interact with receptors in the central nervous system. This interaction suggests that it may have applications in the development of drugs targeting neurological conditions or disorders.
Used in Organic Synthesis Methods:
The production of 4-N-BUTYLBENZAMIDE typically involves organic synthesis methods, which are crucial for obtaining this compound in a pure and stable form. These methods are essential for both research purposes and for scaling up to industrial levels of production.
Check Digit Verification of cas no
The CAS Registry Mumber 107377-07-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,7,3,7 and 7 respectively; the second part has 2 digits, 0 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 107377-07:
(8*1)+(7*0)+(6*7)+(5*3)+(4*7)+(3*7)+(2*0)+(1*7)=121
121 % 10 = 1
So 107377-07-1 is a valid CAS Registry Number.
InChI:InChI=1/C11H15NO/c1-2-3-4-9-5-7-10(8-6-9)11(12)13/h5-8H,2-4H2,1H3,(H2,12,13)
107377-07-1Relevant articles and documents
Copper-catalyzed aerobic oxidative C-C bond cleavage for C-N bond formation: From ketones to amides
Tang, Conghui,Jiao, Ning
, p. 6528 - 6532 (2014)
A novel copper-catalyzed aerobic oxidative C(CO)-C(alkyl) bond cleavage reaction of aryl alkyl ketones for C-N bond formation is described. A series of acetophenone derivatives as well as more challenging aryl ketones with long-chain alkyl substituents could be selectively cleaved and converted into the corresponding amides, which are frequently found in biologically active compounds and pharmaceuticals.
Visible Light-Induced Iodine-Catalyzed Transformation of Terminal Alkynes to Primary Amides via C≡C Bond Cleavage under Aqueous Conditions
Dighe, Shashikant U.,Batra, Sanjay
supporting information, p. 500 - 505 (2016/02/12)
The visible light-induced iodine-catalyzed oxidative cleavage of the C≡C bond for transforming terminal alkynes into primary amides in the presence of ammonia under aqueous conditions is described. This metal-free protocol which ensued via initial hydroamination of the acetylene bond followed by liberation of diiodomethane (CH2I2) was found to be applicable to aromatic, heteroaromatic and aliphatic alkynes.
Discovery and characterization of potent thiazoles versus methicillin- and vancomycin-resistant Staphylococcus aureus
Mohammad, Haroon,Mayhoub, Abdelrahman S.,Ghafoor, Adil,Soofi, Muhammad,Alajlouni, Ruba A.,Cushman, Mark,Seleem, Mohamed N.
, p. 1609 - 1615 (2014/03/21)
Methicillin- and vancomycin-resistant Staphylococcus aureus (MRSA and VRSA) infections are growing global health concerns. Structure-activity relationships of phenylthiazoles as a new antimicrobial class have been addressed. We present 10 thiazole derivatives that exhibit strong activity against 18 clinical strains of MRSA and VRSA with acceptable PK profile. Three derivatives revealed an advantage over vancomycin by rapidly eliminating MRSA growth within 6 h, and no derivatives are toxic to HeLa cells at 11 μg/mL.