107411-29-0

Usage

Uses

Used in Pharmaceutical Synthesis:
1-(4-bromophenyl)-2-methyl-1H-benzo[d]imidazole is used as a building block for the synthesis of pharmaceutical compounds and research chemicals. Its unique structure allows for the creation of various derivatives with potential therapeutic applications.
Used in Anticancer Research:
In the field of oncology, 1-(4-bromophenyl)-2-methyl-1H-benzo[d]imidazole is used as an agent for studying its potential to inhibit the growth of cancer cells. Its biological activities are of interest to researchers seeking novel treatments for various types of cancer.
Used in Antimicrobial Applications:
1-(4-bromophenyl)-2-methyl-1H-benzo[d]imidazole is also used as an antimicrobial agent, leveraging its properties to combat harmful microorganisms. This application is particularly relevant in the development of new antibiotics and antifungal agents to address the growing issue of antibiotic resistance.
Used in Medicinal Chemistry Research:
BIM-1 is utilized in medicinal chemistry research to explore its potential biological activities and to understand its mechanism of action. This research can lead to the discovery of new drugs and therapies for various diseases, including cancer and infectious diseases.

Upstream product

• 615-15-6 2-Methyl-1H-benzimidazole 
• 65826-67-7 bis(4-bromophenyl)iodonium bromide 
• 88348-79-2 di(1H-benzotriazol-1-yl) sulfoxide 
• 609-73-4 o-nitroiodobenzene 
• 103-88-8 4-bromoacetanilide 
• 106-40-1 4-bromo-aniline 
• 760212-66-6 N-[2-(4-bromophenyl amino)-phenyl]-acetamide 
• 43183-36-4 1-(trimethylsilyl)-1H-benzotriazole 
• 125781-66-0 1--1H-benzotriazole 

Relevant academic research and scientific papers

Access to Amidines and Arylbenzimidazoles: Zinc-Promoted Rearrangement of Oxime Acetates

An efficient and straightforward zinc-promoted rearrangement of oxime acetates with arylamines for the synthesis of amidines has been developed under mild conditions. This process involves N?O/C?C bond cleavages and C?C/C?N bond formations. Various oxime

A REGIOSELECTIVE COPPER CATALYZED SYNTHESIS OF BENZIMIDAZOLES AND AZABENZIMIDAZOLES

The present invention relates to a process for the regioselective synthesis of compounds of the formula (I), wherein R0; R1; R2; R3; R4; R5; A1; A2; A3; A4; Q and J have the meanings indicated in the claims. The present invention provides a direct copper catalyzed regioselective process to a wide variety of unsymmetrical, multifunctional N/-substituted benzimidazoles or azabenzimidazoles of formula I starting from 2-halo-nitroarenes and N/-substituted amides. The process is useful for the production of pharmaceuticals, diagnostic agents, liquid crystals, polymers, herbicides, fungicidals, nematicidals, parasiticides, insecticides, acaricides and arthropodicides.

NITROGEN-CONTAINING HETEROCYCLE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT USING THE SAME

A novel derivative of heterocyclic compound having nitrogen atom with a structure made by bonding special groups to benzimidazole, a material for an organic electroluminescence (EL) device comprising the derivative of heterocyclic compound having nitrogen atom and an organic electroluminescence device comprising at least one organic compound layer containing a light emitting layer sandwiched between a pair of electrodes, wherein the device contains the derivative of heterocyclic compound having nitrogen atom. An organic EL device achieving elevation of luminance and of efficiency in light emission even under low driving voltage is obtainable by an employment of the derivative of heterocyclic compound having nitrogen atom for at least one layer composing organic compound layers of the EL device.

Ionic liquid-accelerated N-arylation of benzoazoles with diaryliodonium salts, an efficient method for the synthesis of N-aryl azoles

N-Arylation of benzoazoles with diaryliodonium salts can be performed in good yields in the room-temperature ionic liquid 1-butyl-3-methylimidazolium tetrafluoroborate ([bmim]BF4), which provides an efficient method for the synthesis of N-arylbenzoazoles. The ionic liquid can be recycled and reused.

Synthesis of 1,2-Disubstituted Benzimidazoles by the Photolysis of Imidoylbenzotriazoles

A novel synthesis of 1,2-disubstituted benzimidazoles based on photolysis of imidoylbenzotriazoles is described.