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(S)-4-(5-amino-2-fluorophenyl)-4-methyl-5,6-dihydro-4H-1,3-thiazin-2-amine is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

1075230-69-1

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1075230-69-1 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1075230-69-1 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,7,5,2,3 and 0 respectively; the second part has 2 digits, 6 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 1075230-69:
(9*1)+(8*0)+(7*7)+(6*5)+(5*2)+(4*3)+(3*0)+(2*6)+(1*9)=131
131 % 10 = 1
So 1075230-69-1 is a valid CAS Registry Number.

1075230-69-1Relevant articles and documents

Trifluoromethyl Dihydrothiazine-Based β-Secretase (BACE1) Inhibitors with Robust Central β-Amyloid Reduction and Minimal Covalent Binding Burden

Anan, Kosuke,Iso, Yasuyoshi,Oguma, Takuya,Nakahara, Kenji,Suzuki, Shinji,Yamamoto, Takahiko,Matsuoka, Eriko,Ito, Hisanori,Sakaguchi, Gaku,Ando, Shigeru,Morimoto, Kenji,Kanegawa, Naoki,Kido, Yasuto,Kawachi, Tomoyuki,Fukushima, Tamio,Teisman, Ard,Urmaliya, Vijay,Dhuyvetter, Deborah,Borghys, Herman,Austin, Nigel,Van Den Bergh, An,Verboven, Peter,Bischoff, Francois,Gijsen, Harrie J. M.,Yamano, Yoshinori,Kusakabe, Kenichi

, p. 1894 - 1910 (2019/11/22)

The β-site amyloid precursor protein cleaving enzyme 1 (BACE1, also known as β-secretase) is a promising target for the treatment of Alzheimer's disease. A pKa lowering approach over the initial leads was adopted to mitigate hERG inhibition and

AMINODIHYDROTHIAZINE DERIVATIVES SUBSTITUTED WITH CYCLIC GROUPS

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Page/Page column 35, (2010/02/17)

This invention provides a compound of the formula (I): wherein the ring A is an optionally substituted carbocyclic group or an optionally substituted heterocyclic group; R1 is optionally substituted lower alkyl, optionally substituted lower alk

PHARMACEUTICAL COMPOSITION FOR TREATMENT OF ALZHEIMER'S DISEASE

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Page/Page column 72, (2010/03/02)

A pharmaceutical composition for treating Alzheimer's disease containing a compound represented by the general formula (I): wherein ring A is an optionally substituted carbocyclic group or an optionally substituted heterocyclic group; E is lower alkylene,

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