Cas 1076188-75-4,(S)-N-(3-(2-amino-4-methyl-5,6-dihydro-4H-1,3-thiazin-4-yl)-4-fluorophenyl)-5-methoxypyrazine-2-carboxamide

1076188-75-4

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Basic information

Product Name: (S)-N-(3-(2-amino-4-methyl-5,6-dihydro-4H-1,3-thiazin-4-yl)-4-fluorophenyl)-5-methoxypyrazine-2-carboxamide
Synonyms: (S)-N-(3-(2-amino-4-methyl-5,6-dihydro-4H-1,3-thiazin-4-yl)-4-fluorophenyl)-5-methoxypyrazine-2-carboxamide
CAS NO:1076188-75-4
Molecular Formula:
Molecular Weight: 375.427
EINECS: N/A
Product Categories: N/A

Chemical Properties

Melting Point: N/A
Boiling Point: N/A
Flash Point: N/A
Appearance: N/A
Density: N/A
Refractive Index: N/A
Storage Temp.: N/A
Solubility: N/A
CAS DataBase Reference: (S)-N-(3-(2-amino-4-methyl-5,6-dihydro-4H-1,3-thiazin-4-yl)-4-fluorophenyl)-5-methoxypyrazine-2-carboxamide(CAS DataBase Reference)
NIST Chemistry Reference: (S)-N-(3-(2-amino-4-methyl-5,6-dihydro-4H-1,3-thiazin-4-yl)-4-fluorophenyl)-5-methoxypyrazine-2-carboxamide(1076188-75-4)
EPA Substance Registry System: (S)-N-(3-(2-amino-4-methyl-5,6-dihydro-4H-1,3-thiazin-4-yl)-4-fluorophenyl)-5-methoxypyrazine-2-carboxamide(1076188-75-4)

Safety Data

Hazard Codes: N/A
Statements: N/A
Safety Statements: N/A
WGK Germany:
RTECS:
HazardClass: N/A
PackingGroup: N/A
Hazardous Substances Data: 1076188-75-4(Hazardous Substances Data)

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Check Digit Verification of cas no

The CAS Registry Mumber 1076188-75-4 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,7,6,1,8 and 8 respectively; the second part has 2 digits, 7 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 1076188-75:
(9*1)+(8*0)+(7*7)+(6*6)+(5*1)+(4*8)+(3*8)+(2*7)+(1*5)=174
174 % 10 = 4
So 1076188-75-4 is a valid CAS Registry Number.

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1076188-75-4Relevant academic research and scientific papers

Structure-Based Design of Selective β-Site Amyloid Precursor Protein Cleaving Enzyme 1 (BACE1) Inhibitors: Targeting the Flap to Gain Selectivity over BACE2

Fujimoto, Kazuki,Matsuoka, Eriko,Asada, Naoya,Tadano, Genta,Yamamoto, Takahiko,Nakahara, Kenji,Fuchino, Kouki,Ito, Hisanori,Kanegawa, Naoki,Moechars, Diederik,Gijsen, Harrie J. M.,Kusakabe, Ken-Ichi

, p. 5080 - 5095 (2019/05/28)

BACE1 inhibitors hold potential as agents in disease-modifying treatment for Alzheimer's disease. BACE2 cleaves the melanocyte protein PMEL in pigment cells of the skin and eye, generating melanin pigments. This role of BACE2 implies that nonselective and

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