1075236-89-3

Usage

Uses

Used in Pharmaceutical Industry:
Gepotidacin is used as an antibiotic for the treatment of acute bacterial skin and skin structure infections. It is effective against a wide range of bacterial species, including multidrug-resistant strains, making it a valuable option for treating serious infections.
Used in Urogenital Infections Treatment:
Gepotidacin is used as a treatment for urogenital gonorrhea, a sexually transmitted infection caused by the bacterium Neisseria gonorrhoeae. Its potent activity against this bacterium, even in multidrug-resistant strains, offers a promising solution for managing gonorrhea cases that are resistant to conventional antibiotics.
Used in Combating Antibiotic Resistance:
Gepotidacin is used as a potential new option for the treatment of serious bacterial infections caused by resistant organisms. Its unique mechanism of action and minimal risk of developing resistance make it a valuable addition to the arsenal of antibiotics available to combat antibiotic resistance.

Upstream product

• 527681-61-4 3,4-dihydro-2H-pyrano[2,3-c]pyridine-6-carbaldehyde 
• 1075238-01-5 (2R)-2-[(4-amino-1-piperidinyl)methyl]-1,2-dihydro-3H,8H-2a,5,8a-triazaacenaphthylene-3,8-dione 
• 1075237-99-8 1,1-dimethylethyl {1-[(3,8-dioxo-1,2-dihydro-3H,8H-2a,5,8a-triazaacenaphthylen-2-yl)methyl]-4-piperidinyl}carbamate 
• 1075237-93-2 ethyl N-[2-[(2,2-dimethyl-1,3-dioxan-5-yl)amino]-6-(methyloxy)-3-pyridinyl]glycinate 
• 1075237-94-3 4-(2,2-dimethyl-1,3-dioxan-5-yl)-6-(methyloxy)-1,4-dihydropyrido[2,3-b]pyrazin-3(2H)-one 
• 1075237-96-5 4-(2,2-dimethyl-1,3-dioxan-5-yl)-6-(methyloxy)pyrido[2,3-b]pyrazin-3(4H)-one 
• 1075237-97-6 4-[2-hydroxy-1-(hydroxymethyl)ethyl]-6-(methyloxy)pyrido[2,3-b]pyrazin-3(4H)-one 
• 1075237-92-1 N²-(2,2-dimethyl-1,3-dioxan-5-yl)-6-(methyloxy)-2,3-pyridinediamine 
• 1075237-91-0 N-(2,2-dimethyl-1,3-dioxan-5-yl)-6-(methyloxy)-3-nitro-2-pyridinamine 
• 38533-61-8 2-chloro-6-methoxy-3-nitropyridine 
• 757186-96-2 2-{[6-(methyloxy)-3-nitro-2-pyridinyl]amino}-1,3-propanediol 

Relevant academic research and scientific papers

Methods for treating neisseria gonorrhoeae infection with substituted 1,2-dihydro-2A,5,8A-triazaacenaphthylene-3,8-diones

The present invention relates to methods for treating Neisseria Gonorrhoeae infection which comprises administering to a subject in need thereof novel 1,2-dihydro-2a,5,8a-triazaacenaphthylene-3,8-dione compounds: or pharmaceutically acceptable salts thereof and/or corresponding pharmaceutical compositions.

TRICYCLIC NITROGEN CONTAINING COMPOUNDS AS ANTIBACTERIAL AGENTS

Tricyclic nitrogen containing compounds and their use as antibacterials. Z1and Z2 are independently selected from CH and N.