107554-42-7Relevant articles and documents
Regio- and enantioselective synthesis of novel functionalized pyranopyrrolidines by 1,3-dipolar cycloaddition of carbohydrates
Bashiardes, George,Cano, Céline,Mauzé, Bernard
, p. 587 - 590 (2005)
A new methodology is described for the rapid enantiomeric synthesis of a novel series of pyranopyrrolidines from readily available and inexpensive carbohydrate compounds. The major feature of the method is a highly selective [3+2] cycloaddition reaction of different azomethine ylides with a chiral carbohydrate-derived enone. The reaction proved to be extremely regio- and stereoselective, giving rise to single enantiomeric compounds in all cases. Moreover, the method is totally atom-efficient and amenable to diversity, since structural diversity of the new compounds is dictated by the choice of the starting materials employed.
Diastereoselective Strecker Synthesis using α-Phenylglycinol as Chiral Auxiliary
Chakraborty, T. K.,Reddy, G. V.,Hussain, K. Azhar
, p. 7597 - 7600 (2007/10/02)
Use of α-phenylglycinol as chiral auxiliary in Strecker synthesis ensures high diastereoselectivity and its easy removal by oxidative cleavage allows large scale preparation of optically active α-amino acids.
