1075748-44-5

Basic information

• Product Name: 1,2-diamino-3,5-dimethoxybenzene
• CAS NO: 1075748-44-5
• Molecular Weight: 168.195
• Mol File: 1075748-44-5.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 1,2-diamino-3,5-dimethoxybenzene(CAS DataBase Reference)
• NIST Chemistry Reference: 1,2-diamino-3,5-dimethoxybenzene(1075748-44-5)
• EPA Substance Registry System: 1,2-diamino-3,5-dimethoxybenzene(1075748-44-5)

Safety Data

• Hazardous Substances Data: 1075748-44-5(Hazardous Substances Data)

Usage

Appearance

White to off-white solid

Solubility

Soluble in polar organic solvents

Uses

a. Building block for pharmaceuticals and fine chemicals
b. Potential use in novel materials development
c. Precursor for organic dyes synthesis

Biological activities

a. Antimicrobial properties
b. Antifungal properties

Potential applications

a. Development of pharmaceuticals
b. Antimicrobial agents

Upstream product

• 1353562-24-9 N-(3,5-dimethoxyphenyl)formamide 
• 109069-76-3 3,5-dimethoxy-2-nitrobenzoyl chloride 
• 113884-71-2 Acide 2-nitro-3,5-dimethoxybenzoique 
• 192696-43-8 3,5-Dimethoxy-2-nitrobenzenamine 

Relevant articles and documents

Synthesis of dimethoxy activated benzimidazoles and bisbenzimidazoles

A range of 2-substituted-4,6-dimethoxy activated benzimidazoles and 2,2'-bisbenzimidazoles have been synthesized from 2-aminoanilide derivatives under acidic conditions. The starting materials were prepared either by acylation from 3,5-dimethoxyaniline followed by nitration, or by acylation from 3,5-dimethoxy-2-nitroaniline. The 2-nitroanilides were then reduced by palladium catalyzed reaction with hydrazine and subsequent acid catalyzed cyclization giving the corresponding 4,6-dimethoxybenzimidazoles and 4,6-dimethoxy-2,2'-bisbenzimidazoles. In addition, 2-phenyl-4,5,6-trimethoxybenzimidazole has been synthesized using a similar procedure.

BRIDGED SIX-MEMBERED RING COMPOUNDS

The invention relates to compounds of formula (I), wherein R1, R2, R1a, R2a, R3, R4, A, B, X, W and n are as defined in the description, and pharmaceutically acceptable salts of such compounds. These compounds are useful as calcium channel blockers.