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1075753-27-3

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1075753-27-3 Usage

General Description

1H-Benzimidazole, 2-chloro-7-(trifluoromethyl)- is a chemical compound with the molecular formula C9H4ClF3N2. It is a benzimidazole derivative with a chlorine atom and a trifluoromethyl group attached to the 2nd and 7th carbon atoms, respectively. 1H-Benzimidazole, 2-chloro-7-(trifluoromethyl)- is often used in pharmaceutical and research applications, where it has been found to exhibit various biological activities, including antifungal, antibacterial, and antiproliferative properties. Its unique molecular structure and functional groups make it a valuable building block for the synthesis of diverse organic compounds. Additionally, its potential medicinal properties make it a target for drug discovery and development.

Check Digit Verification of cas no

The CAS Registry Mumber 1075753-27-3 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,7,5,7,5 and 3 respectively; the second part has 2 digits, 2 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 1075753-27:
(9*1)+(8*0)+(7*7)+(6*5)+(5*7)+(4*5)+(3*3)+(2*2)+(1*7)=163
163 % 10 = 3
So 1075753-27-3 is a valid CAS Registry Number.

1075753-27-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-chloro-4-(trifluoromethyl)-1H-benzimidazole

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1075753-27-3 SDS

1075753-27-3Downstream Products

1075753-27-3Relevant articles and documents

Benzenesulfonamide IDH mutant inhibitor, preparation method and application thereof

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Paragraph 0069; 0084-0086, (2020/09/23)

The invention discloses a benzenesulfonamide compound represented by a general formula (I) or a pharmaceutically acceptable salt thereof, a preparation method and application thereof. Compared with the prior art, the benzenesulfonamide compound disclosed by the invention can be used as an isocitrate dehydrogenase 2 (IDH2) mutant inhibitor. According to the invention, pharmacological experiment results show that the compound disclosed by the invention has an obvious inhibiting effect on the activity of an IDH2 mutant (mIDH2), can effectively inhibit the process of catalyzing alpha-ketoglutaricacid to generate 2-hydroxyglutaric acid by mIDH2, and can be used for preventing and/or treating various related diseases including cancers and the like caused by IDH2 mutation.

QUINUCLIDINE COMPOUNDS AS ALPHA-7 NICOTINIC ACETYLCHOLINE RECEPTOR LIGANDS

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Page/Page column 59, (2016/06/01)

There are disclosed a series of quinuclidines having the Formula (I). which bind to the nicotinic α7 receptor and may be useful for the treatment of disorders of the central nervous system.

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