107599-40-6

Basic information

• Product Name: METHYL 1-ETHYLPYRROLIDINE-2-CARBOXYLATE
• Synonyms: METHYL 1-ETHYLPYRROLIDINE-2-CARBOXYLATE;L-Proline, 1-ethyl-, methyl ester (9CI);Methyl 1-ethylpyrrolidine-2-carboxylate 97%;Methyl (2S)-1-ethylpyrrolidine-2-carboxylate 97%;(2S)-1-Methyl-2-(methoxycarbonyl)pyrrolidine;methyl (2S)-1-ethylpyrrolidine-2-carboxylate
• CAS NO: 107599-40-6
• Molecular Formula: C8H15NO2
• Molecular Weight: 157.21
• Product Categories: PYRROLE
• Mol File: 107599-40-6.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 188.2 °C at 760 mmHg
• Flash Point: 66.8 °C
• Appearance: /
• Density: 1.014 g/cm³
• Vapor Pressure: 0.608mmHg at 25°C
• Refractive Index: 1.458
• CAS DataBase Reference: METHYL 1-ETHYLPYRROLIDINE-2-CARBOXYLATE(CAS DataBase Reference)
• NIST Chemistry Reference: METHYL 1-ETHYLPYRROLIDINE-2-CARBOXYLATE(107599-40-6)
• EPA Substance Registry System: METHYL 1-ETHYLPYRROLIDINE-2-CARBOXYLATE(107599-40-6)

Safety Data

• Hazard Codes: Xi
• Hazardous Substances Data: 107599-40-6(Hazardous Substances Data)

Usage

General Description

Methyl 1-ethylpyrrolidine-2-carboxylate is a chemical compound that belongs to the class of pyrrolidine carboxylates. It is a derivative of pyrrolidine, a five-membered heterocyclic compound containing a nitrogen atom. This chemical is commonly used as an intermediate in the synthesis of pharmaceutical compounds and other organic molecules. Its properties and applications are primarily based on its structure and reactivity, which make it suitable for various chemical reactions and processes in the pharmaceutical and chemical industries. Methyl 1-ethylpyrrolidine-2-carboxylate has potential uses in drug development, agrochemicals, and other fields where the synthesis of complex organic molecules is required.

InChI:InChI=1/C8H15NO2/c1-3-9-6-4-5-7(9)8(10)11-2/h7H,3-6H2,1-2H3

Upstream product

• 2133-40-6 L-proline methyl ester monohydrochloride 
• 75-07-0 acetaldehyde 
• 147-85-3 L-proline 
• 27460-51-1 N-acetyl-proline methyl ester 
• 533-88-0 2-amino-5-hydroxyvaleric acid 
• 7335-06-0 1-ethylpyrrolidine 
• 616-38-6 carbonic acid dimethyl ester 
• 74-96-4 ethyl bromide 
• 2133-40-6 methyl pyrrolidine-2-carboxylate hydrochloride 
• 62-50-0 Ethyl methanesulfonate 

Downstream Products

• 98435-76-8 (S)-1-ethyl-pyrrolidine-2-carboxylic acid 
• 73058-14-7 methyl 1-ethyl-1H-pyrrole-2-carboxylate 

Relevant articles and documents

Preparation method of (s)-N-ethyl-2-aminomethylpyrrolidine

The invention provides a preparation method of (s)-N-ethyl-2-aminomethylpyrrolidine. 2-amino-5-hydroxyvaleric acid used as a raw material undergoes esterification protection to obtain methyl 2-amino-5-hydroxypentanoate, N-ethylation is further achieved through bromoethane, and then the N-ethyl-2-aminomethylpyrrolidine is prepared through hydroxyl halogenation, substitution cyclization, ammonolysisand reduction six-step reaction. High-cost raw materials and an N,O-diethylation reaction are successfully avoided, and the method has the advantages of easiness in implementation of the above reaction route, few byproducts, high yield reaching 64.2%, and suitableness for industrialization.

Synthesis of Lepadiformine Using a Hydroamination Transform

Dissection of lepadiformine by a double hydroamination transform affords a simple achiral amino diene. This reaction is accomplished in the forward sense by amine-directed hydroboration and an oxidative alkyl shift to nitrogen, both of which occur with hi

SUBSTITUTED BENZAMIDE MODULATORS OF DOPAMINE RECEPTOR

The present invention relates to new substituted benzamide modulators of dopamine receptor, pharmaceutical compositions thereof, and methods of use thereof.