62-50-0 Usage
Chemical Properties
Different sources of media describe the Chemical Properties of 62-50-0 differently. You can refer to the following data:
1. colourless liquid
2. Ethyl methane sulfonate is a clear liquid.
Uses
Different sources of media describe the Uses of 62-50-0 differently. You can refer to the following data:
1. Experimentally as mutagen, teratogen and brain carcinogen.
2. Ethyl methanesulfonate is used as mutagen for both mammalian and plant cells. It finds application as a model alkylating agent in the study of deoxyribonucleic acid (DNA) repair processes.
Definition
ChEBI: A methanesulfonate ester resulting from the formal condensation of methanesulfonic acid with ethanol.
General Description
Clear colorless liquid. Denser than water.
Air & Water Reactions
Water soluble.
Reactivity Profile
Ethyl methanesulfonate alkylates nucleophiles such as hydroxy, amino and sulfhydryl groups in model and biological materials. Is hydrolyzed by excess aqueous alkali to non-corrosive and non-toxic products. Is hydrolyzed by water to a highly corrosive product .
Fire Hazard
Ethyl methanesulfonate is combustible.
Biochem/physiol Actions
Ethyl methanesulfonate is a DNA ethylating agent, mutagenic to plants and animals and carcinogenic in mammals. It has been used as a model alkylating agent in studies of DNA repair processes. EMS induces base substitutions of guanine-cytosine (G/C) to adenine-thymine (A/T). EMS also generates point mutations and single nucleotide polymorphisms in genomes. EMS is potential chemical mutagen used for inducing mutation in rice, wheat and Arabidopsis thaliana.
Safety Profile
Confirmed carcinogen
with experimental carcinogenic,
neoplas tigenic, tumorigenic, and teratogenic
data. Poison by ingestion and intraperitoneal
routes. Experimental reproductive effects.
Human mutation data reported. When
heated to decomposition it emits toxic
fumes of SOx. See also SULFONATES and
ESTERS.
Potential Exposure
Used as a research tool for mutagenesis and carcinogenesis studies. Was considered as a possible
human male contraceptive. Also considered as a reversible
male hemosterilant for insects and mammalian pests.
Carcinogenicity
Ethyl methanesulfonate is reasonably anticipated to be a human carcinogen based on sufficient evidence of carcinogenicity from studies in experimental animals.
Incompatibilities
Vapors may form explosive mixture with
air. Incompatible with oxidizers (chlorates, nitrates, peroxides, permanganates, perchlorates, chlorine, bromine, fluorine, etc.); contact may cause fires or explosions. Keep
away from alkaline materials, strong bases, strong acids,
oxoacids, and epoxides. Contact with moisture may cause
hydrolysis or other forms of decomposition
Check Digit Verification of cas no
The CAS Registry Mumber 62-50-0 includes 5 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 2 digits, 6 and 2 respectively; the second part has 2 digits, 5 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 62-50:
(4*6)+(3*2)+(2*5)+(1*0)=40
40 % 10 = 0
So 62-50-0 is a valid CAS Registry Number.
InChI:InChI=1/C3H8O3S/c1-3-6-7(2,4)5/h3H2,1-2H3
62-50-0Relevant articles and documents
Additive, electrolyte for rechargeable lithium battery, and rechargeable lithium battery
-
Paragraph 0131-0135, (2021/01/29)
An additive, an electrolyte for a rechargeable lithium battery, and a rechargeable lithium battery, the additive being represented by Chemical Formula 1.
Exploiting 1,2,3-Triazolium Ionic Liquids for Synthesis of Tryptanthrin and Chemoselective Extraction of Copper(II) Ions and Histidine-Containing Peptides
Li, Hsin-Yi,Chen, Chien-Yuan,Cheng, Hui-Ting,Chu, Yen-Ho
, (2016/11/02)
Based on a common structural core of 4,5,6,7-Tetrahydro[1,2,3]triazolo[1,5-A]pyridine, a number of bicyclic triazolium ionic liquids 1-3 were designed and successfully prepared. In our hands, this optimized synthesis of ionic liquids 1 and 2 requires no chromatographic separation. Also in this work, ionic liquids 1, 2 were shown to be efficient ionic solvents for fast synthesis of tryptanthrin natural product. Furthermore, a new affinity ionic liquid 3 was tailor-synthesized and displayed its effectiveness in chemoselective extraction of both Cu(II) ions and, for the first time, histidine-containing peptides.
Physicochemical characterization of new sulfonate and sulfate ammonium ionic liquids
Mahrova, Maria,Vilas, Miguel,Dominguez, Angeles,Gomez, Elena,Calvar, Noelia,Tojo, Emilia
scheme or table, p. 241 - 248 (2012/05/20)
In this work we describe the synthesis and thermal properties of nine new salts derived from ammonium that incorporate alkanesulfonate and alkanesulfate anions. Their structures were confirmed by 1H and 13C NMR and HRMS-ESI. Their thermal properties were determined by differential scanning calorimetry (DSC). Three of the synthesized salts have been shown to be room temperature ionic liquids: N-ethyl-N-(2-hydroxyethyl)-N,N-dimethylammonium butanesulfonate, N-ethyl-N,N-dimethylbutylammonium ethylsulfate, and N-ethyl-N-(2-hydroxyethyl)-N,N-dimethylammonium ethylsulfate. Experimental densities, speeds of sound, dynamic viscosities, and refractive indices of these three ionic liquids were measured at T = 298.15 K.