1076-47-7

Basic information

• Product Name: 2,3,4-TRIMETHYLBENZOICACID
• Synonyms: 2,3,4-TRIMETHYLBENZOICACID
• CAS NO: 1076-47-7
• Molecular Formula: C₁₀H₁₂O₂
• Molecular Weight: 164.20108
• Mol File: 1076-47-7.mol
• Article Data: 4

Chemical Properties

• Melting Point: 105.65°C (estimate)
• Boiling Point: 288.61°C (estimate)
• Flash Point: 143.5°C
• Appearance: /
• Density: 1.0670 (estimate)
• Vapor Pressure: 0.000256mmHg at 25°C
• Refractive Index: 1.5198 (estimate)
• CAS DataBase Reference: 2,3,4-TRIMETHYLBENZOICACID(CAS DataBase Reference)
• NIST Chemistry Reference: 2,3,4-TRIMETHYLBENZOICACID(1076-47-7)
• EPA Substance Registry System: 2,3,4-TRIMETHYLBENZOICACID(1076-47-7)

Safety Data

• Hazardous Substances Data: 1076-47-7(Hazardous Substances Data)

Usage

General Description

2,3,4-Trimethylbenzoic acid is a chemical compound with the molecular formula C10H12O2. It is a derivative of benzoic acid and it consists of a benzene ring with three methyl groups attached at the 2, 3, and 4 positions. 2,3,4-TRIMETHYLBENZOICACID is a white crystalline powder that is insoluble in water but soluble in organic solvents. 2,3,4-Trimethylbenzoic acid is commonly used in the synthesis of pharmaceuticals, as well as in the production of various fragrances and flavoring agents. It has also been studied for its potential anti-inflammatory and antimicrobial properties, making it a valuable compound in the field of medicinal chemistry.

InChI:InChI=1/C10H12O2/c1-6-4-5-9(10(11)12)8(3)7(6)2/h4-5H,1-3H3,(H,11,12)

Upstream product

• 488-23-3 1,2,3,4-Tetramethylbenzene 
• 526-73-8 1,2,3-trimethylbenzene 
• 75-36-5 acetyl chloride 
• 60367-94-4 2.3.4-Trimethylbenzylnitrat 
• 60368-02-7 Methyl-2,3,4-trimethylbenzylether 
• 60392-10-1 2,3,4-Trimethylbenzylacetat 
• 1086-70-0 3-(2.3,4-Trimethyl-benzoyl)-propionsaeure-aethylester 
• 854180-50-0 2,3,4-trimethyl-benzyl alcohol 
• 7697-37-2 nitric acid 
• 509-14-8 tetranitromethane 
• 1082-77-5 3-(2,3,4-Trimethylbenzoyl)propionsaeure 
• 124-38-9 carbon dioxide 

Downstream Products

• 190367-55-6 5-Methanesulfonyl-2,3,4-trimethyl-benzoic acid methyl ester 
• 13667-30-6 2,3,4-trimethyl-5-nitrobenzoic acid 
• 1416990-28-7 C₁₄H₂₀BrNO 
• 90918-98-2 2,3,4-trimethyl-benzoyl chloride 
• 1416990-27-6 C₁₄H₂₁NO 
• 112277-84-6 amino-4 bromo-5 hemimellitene 
• 112277-74-4 Trimethyl-(3,4,5-trimethyl-phenyl)-silane 
• 1467-35-2 2,3,4-trimethylaniline 
• 32591-43-8 5-bromo-1,2,3-trimethylbenzene 
• 112277-80-2 azidocarbonyl-4 hemimellitene 

Relevant articles and documents

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Isosteric analogs of lenalidomide and pomalidomide: Synthesis and biological activity

A series of analogs of the immunomodulary drugs lenalidomide (1) and pomalidomide (2), in which the amino group is replaced with various isosteres, was prepared and assayed for immunomodulatory activity and activity against cancer cell lines. The 4-methyl and 4-chloro analogs 4 and 15, respectively, displayed potent inhibition of tumor necrosis factor-α (TNF-α) in LPS-stimulated hPBMC, potent stimulation of IL-2 in a human T cell co-stimulation assay, and anti-proliferative activity against the Namalwa lymphoma cell line. Both of these analogs displayed oral bioavailability in rat.

Hydrocarbures arylaliphatiques. Partie VIII. Etude cinetique de la protodesilylation de benzocyclenes tricycliques

A kinetic study of the protodesilylation of silylated derivatives of hemimellitene, 2a,3,4,5 tetrahydro acenaphthene and 1H 2,2a,3,4,5,6 hexahydro benzo(c,d)azulene is described.These results complete those published previously and which are related to the influence of the ring size of alicyclic systems pericondensed to a benzene nucleus on the reactivity of the nucleus to acetylation or bromination.The silylated derivatives were prepared from the corresponding bromo compounds.The synthesis of the bromo compounds, some of which were described in an earlier study, is completed here by using a synthetic pathway which allows the preparation of the β isomers starting from the ortho bromo derivatives.The kinetic results show a deactivation of the β position of the hemimellitene.A little deactivation of ortho α position of the five membered ring in the tricyclic compounds is also observed.This last result, significant in the case of bromination, seems to be related to the Mills-Nixon effect and can be explained by using Streitwieser's hybridization for the ? skeleton.