1076206-75-1Relevant academic research and scientific papers
Copper-catalyzed addition reactions of aromatics and ketones to 2-aza-2,4-cyclopentadienone: Facile and efficient transformation of carbonyl-ene-nitriles to 1H-pyrrolin-2(5H)-ones
Murai, Masahito,Miki, Koji,Ohe, Kouichi
supporting information; experimental part, p. 9174 - 9176 (2009/04/06)
(Chemical Equation Presented) Copper-catalyzed reactions of carbonyl-ene-nitriles with carbon nucleophiles, such as aromatics and ketones, afforded pyrrolin-2-ones (γ-lactam) in excellent yield. The reaction mechanism involves addition reactions with a ke
