1078052-82-0

Basic information

• Product Name: C₂₃H₃₅NO₇
• Synonyms: C₂₃H₃₅NO₇
• CAS NO: 1078052-82-0
• Molecular Weight: 437.533
• Mol File: 1078052-82-0.mol

Chemical Properties

• CAS DataBase Reference: C₂₃H₃₅NO₇(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₃H₃₅NO₇(1078052-82-0)
• EPA Substance Registry System: C₂₃H₃₅NO₇(1078052-82-0)

Safety Data

• Hazardous Substances Data: 1078052-82-0(Hazardous Substances Data)

Upstream product

• 500788-93-2 3-(tert-butoxycarbonylamino)-3-(3,4-dimethoxyphenyl)propanoic acid 
• 5763-61-1 3,4-dimethoxybenzylamine 
• 34840-85-2 3-amino-3-(3,4-dimethoxyphenyl)propanoic acid 
• 120-14-9 3,4-dimethoxy-benzaldehyde 
• 78-77-3 Isobutyl bromide 
• 1078052-80-8 methyl 5-(tert-butoxycarbonylamino)-5-(3,4-dimethoxyphenyl)-3-oxopentanoate 

Downstream Products

• 1078052-84-2 6-(3,4-dimethoxyphenyl)-4-isobutoxy-5,6-dihydropyridin-2(1H)-one 
• 1078052-83-1 C₁₇H₂₃NO₄ 

Relevant articles and documents

GLUCOSE METABOLISM MODULATING COMPOUNDS

The present invention provides, inter alia, dihydropyridone compounds and compositions, including analogs of a vesicular monoamine transporter type 2 (VMAT2) antagonist. The present invention also provides methods of using such compounds/analogs for modulating glucose levels, and/or preventing, treating, or ameliorating the effects of diabetes and hyperglycemia.

HYPOGLYCEMIC DIHYDROPYRIDONES

The present invention provides, inter alia, a compound of formula I: wherein the substituent designations are indicated in the Specification. The present invention also provides pharmaceutical compositions comprising a compound of formula I, and methods o

Novel hypoglycemic dihydropyridones serendipitously discovered from O- versus C-alkylation in the synthesis of VMAT2 antagonists

Vesicular monoamine transporter type 2 (VMAT2) is a newly emerging target for both diagnostic and therapeutic applications in diabetes mellitus. In pursuit of novel VMAT2 antagonists, we identified a potent hypoglycemic agent with a novel dihydropyridone