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(R)-BOC-3 4-DIMETHOXY-BETA-PHE-OH, also known as (R)-tert-butoxycarbonyl-3-(2,4-dimethoxybenzyl)-D-phenylalanine, is a BOC-protected amino acid with chiral and aromatic properties. It is characterized by the presence of a BOC group that protects the amine functional group, enabling selective deprotonation and coupling reactions. The 2,4-dimethoxybenzyl and D-phenylalanine groups contribute to its unique structure, making it a valuable component in the synthesis of complex and biologically active peptides.

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  • (R)-3-((TERT-BUTOXYCARBONYL)AMINO)-3-(3,4-DIMETHOXYPHENYL)PROPANOIC ACID

    Cas No: 500788-93-2

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  • 500788-93-2 Structure
  • Basic information

    1. Product Name: (R)-BOC-3 4-DIMETHOXY-BETA-PHE-OH
    2. Synonyms: (r)-boc-3,4-dimethoxy-β-phe-oh;Boc-D-b-Phe(3,4-dimethoxy)-OH;(R)-3-(Boc-amino)-3-(3,4-methoxyphenyl)propionic acid, Boc-3,4-dimethoxy-L-β-phenylalanine;Boc-3,4-DiMethoxy-D-b-phenylalanine;(R)-3-((TERT-BUTOXYCARBONYL)AMINO)-3-(3,4-DIMETHOXYPHENYL)PROPANOIC ACID;(Tert-Butoxy)Carbonyl (R)-3-Amino-3-(3,4-dimethoxy-phenyl)propionic acid
    3. CAS NO:500788-93-2
    4. Molecular Formula: C16H23NO6
    5. Molecular Weight: 325.359
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 500788-93-2.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: 2-8°C
    8. Solubility: N/A
    9. CAS DataBase Reference: (R)-BOC-3 4-DIMETHOXY-BETA-PHE-OH(CAS DataBase Reference)
    10. NIST Chemistry Reference: (R)-BOC-3 4-DIMETHOXY-BETA-PHE-OH(500788-93-2)
    11. EPA Substance Registry System: (R)-BOC-3 4-DIMETHOXY-BETA-PHE-OH(500788-93-2)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany: 3
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 500788-93-2(Hazardous Substances Data)

500788-93-2 Usage

Uses

Used in Pharmaceutical Industry:
(R)-BOC-3 4-DIMETHOXY-BETA-PHE-OH is used as a building block for the preparation of various peptide-based pharmaceuticals and bioactive molecules. Its chiral and aromatic properties, along with the protective BOC group, make it a crucial component in the synthesis of diverse peptide-based compounds with potential pharmaceutical and biological applications.
Used in Peptide Synthesis:
(R)-BOC-3 4-DIMETHOXY-BETA-PHE-OH is used as a key component in peptide synthesis, where the BOC group provides protection for the amine functional group, allowing for selective deprotonation and subsequent coupling reactions. This enables the formation of complex peptide structures with desired biological activities.

Check Digit Verification of cas no

The CAS Registry Mumber 500788-93-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 5,0,0,7,8 and 8 respectively; the second part has 2 digits, 9 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 500788-93:
(8*5)+(7*0)+(6*0)+(5*7)+(4*8)+(3*8)+(2*9)+(1*3)=152
152 % 10 = 2
So 500788-93-2 is a valid CAS Registry Number.

500788-93-2 Well-known Company Product Price

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  • (08009)  (R)-Boc-3,4-dimethoxy-β-Phe-OH  ≥98.0%

  • 500788-93-2

  • 08009-500MG-F

  • 3,638.70CNY

  • Detail

500788-93-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 13, 2017

Revision Date: Aug 13, 2017

1.Identification

1.1 GHS Product identifier

Product name (R)-Boc-3,4-dimethoxy-β-Phe-OH

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:500788-93-2 SDS

500788-93-2Relevant articles and documents

GLUCOSE METABOLISM MODULATING COMPOUNDS

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, (2016/11/14)

The present invention provides, inter alia, dihydropyridone compounds and compositions, including analogs of a vesicular monoamine transporter type 2 (VMAT2) antagonist. The present invention also provides methods of using such compounds/analogs for modulating glucose levels, and/or preventing, treating, or ameliorating the effects of diabetes and hyperglycemia.

HYPOGLYCEMIC DIHYDROPYRIDONES

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Page/Page column 57, (2010/04/03)

The present invention provides, inter alia, a compound of formula I: wherein the substituent designations are indicated in the Specification. The present invention also provides pharmaceutical compositions comprising a compound of formula I, and methods o

New entry to the asymmetric synthesis of (-)-lasubine I and (+)-subcosine I

Yamazaki, Naoki,Atobe, Masakazu,Kibayashi, Chihiro,Aoyagi, Sakae

scheme or table, p. 433 - 439 (2009/12/05)

A new synthetic entry to (-)-lasubine I and (+)-subcosine I has been established by employing the (S)-allylalkoxy benzylamine as a chiral synthon. The synthesis involves the formation of an α,β-unsaturated lactone by RCM reaction followed by an intramolec

Novel hypoglycemic dihydropyridones serendipitously discovered from O- versus C-alkylation in the synthesis of VMAT2 antagonists

Xie, Yuli,Raffo, Anthony,Ichise, Masanori,Deng, Shixian,Harris, Paul E.,Landry, Donald W.

scheme or table, p. 5111 - 5114 (2009/07/18)

Vesicular monoamine transporter type 2 (VMAT2) is a newly emerging target for both diagnostic and therapeutic applications in diabetes mellitus. In pursuit of novel VMAT2 antagonists, we identified a potent hypoglycemic agent with a novel dihydropyridone

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