107920-31-0

Basic information

• Product Name: N-(1,1-dioxido-1,2-benzisothiazol-3-yl)-N-(4-methoxyphenyl)amine
• Synonyms: N-(1,1-dioxido-1,2-benzisothiazol-3-yl)-N-(4-methoxyphenyl)amine
• CAS NO: 107920-31-0
• Molecular Formula: C₁₄H₁₂N₂O₃S
• Molecular Weight: 288.32168
• Mol File: 107920-31-0.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: N-(1,1-dioxido-1,2-benzisothiazol-3-yl)-N-(4-methoxyphenyl)amine(CAS DataBase Reference)
• NIST Chemistry Reference: N-(1,1-dioxido-1,2-benzisothiazol-3-yl)-N-(4-methoxyphenyl)amine(107920-31-0)
• EPA Substance Registry System: N-(1,1-dioxido-1,2-benzisothiazol-3-yl)-N-(4-methoxyphenyl)amine(107920-31-0)

Safety Data

• Hazardous Substances Data: 107920-31-0(Hazardous Substances Data)

Upstream product

• 134-20-3 2-carbomethoxyaniline 
• 119300-80-0 2-methoxycarbonyl-benzenesulfinic acid 
• 57683-71-3 methyl 2-(aminosulfonyl)benzoate 
• 81-07-2 saccharin 
• 371779-94-1 N,N-bis(1,1-dioxo-1,2-benzisothiazol-3-yl)-4-methoxyaniline 
• 104-94-9 4-methoxy-aniline 
• 567-19-1 3-chloro-1,2-benzisothiazole 1,1-dioxide 

Downstream Products

• 371779-94-1 N,N-bis(1,1-dioxo-1,2-benzisothiazol-3-yl)-4-methoxyaniline 

Relevant articles and documents

Synthesis, characterization and antimicrobial evaluation of new 3-(Alkyl/Arylamino)benzo[d]isothiazole 1,1-derivatives

The saccharine nucleus has long been recognized as a significant component in medicine. A series of pseudo-saccharine amines derivatives (7a-j) were synthesized and examined for their antibacterial activity. After testing all compounds, 7b, 7f, 7g, 7i and 7j were found most effective against Escherichia coli, Streptococcus aureus and Bacillus subtilis strains. The MIC of the compound was found from 4.6 to 16.1 μM. Further, compound 7f and 7i exhibited excellent activity against E.coli and Bacillus subtilis with MIC value 4.6 and 4.7 μM respectively. The compound 7b and 7i was found active against all the three bacteria. The zone inhibition was observed at 10 μM against Escherichia coli, Staphylococcus aureus and Bacillus subtilis at 0.9, 1.8, 3.9 respectively for 7b and 1.0, 1.8 and 2.0 cm respectively for 7i.

Synthesis and Spectroscopic Properties of Some New Substituted Saccharin Anils

Fourteen new substituted saccharin anils have been synthesized by the reaction of pseudosaccharin chloride with various substituted anilines.The IR, proton NMR, and carbon-13 NMR spectral properties are presented and discussed.