1079277-94-3

Basic information

• Product Name: C₁₉H₃₀O₅Si
• Synonyms: C₁₉H₃₀O₅Si
• CAS NO: 1079277-94-3
• Molecular Weight: 366.53
• Mol File: 1079277-94-3.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: C₁₉H₃₀O₅Si(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₉H₃₀O₅Si(1079277-94-3)
• EPA Substance Registry System: C₁₉H₃₀O₅Si(1079277-94-3)

Safety Data

• Hazardous Substances Data: 1079277-94-3(Hazardous Substances Data)

Upstream product

• 100-51-6 benzyl alcohol 
• 4511-42-6 L,L-dilactide 
• 923-17-1 (S,S)-2-[(2-hydroxypropanoyl)oxy]propanoic acid 
• 188776-87-6 tert-butyldimethylsiloxylactoyl lactic acid 
• 56777-24-3 benzyl (S)-Lactate 
• 314069-33-5 (S)-2-hydroxy-propionic acid (S)-1-benzyloxycarbonyl-ethyl ester 
• 18162-48-6 tert-butyldimethylsilyl chloride 

Downstream Products

• 909025-02-1 C₂₂H₃₄O₇Si 
• 909025-03-2 C₂₅H₃₈O₉Si 
• 909025-06-5 C₂₈H₄₂O₁₁Si 
• 909025-08-7 C₃₄H₅₀O₁₅Si 
• 909025-07-6 C₃₁H₄₆O₁₃Si 
• 909025-11-2 (2S)-1-{[(2S)-1-{[(2S)-1-{[(2S)-1-{[(2S)-1-(benzyloxy)-1-oxopropan-2-yl]oxy}-1-oxopropan-2-yl]oxy}-1-oxopropan-2-yl]oxy}-1-oxopropan-2-yl]oxy}-1-oxopropan-2-yl (2S)-2-hydroxypropanoate 
• 1396314-79-6 6-[(S)-2-((S)-2-(tertbutyldimethylsilyloxy)propanoyloxy)propanoate] hexanoic benzyl ester 
• 1396314-81-0 6-[(S)-2-((S)-2-hydroxypropanoyloxy)propanoate]hexanoic benzyl ester 
• 1396314-82-1 C₃₇H₅₈O₁₃Si 
• 909025-05-4 (S)-2-hydroxypropionic acid (S)-1-[(S)-1-((S)-1-benzyloxycarbonylethoxycarbonyl)ethoxycarbonyl]ethyl ester 

Relevant articles and documents

Hydrophilic Oligo(lactic acid)s Captured by a Hydrophobic Polyaromatic Cavity in Water

Biologically relevant hydrophilic molecules rarely interact with hydrophobic compounds and surfaces in water owing to effective hydration. Nevertheless, herein we report that the hydrophobic cavity of a polyaromatic capsule, formed through coordination-driven self-assembly, can encapsulate hydrophilic oligo(lactic acid)s in water with relatively high binding constants (up to Ka=3×105 m?1). X-ray crystallographic and ITC analyses revealed that the unusual host–guest behavior is caused by enthalpic stabilization through multiple CH–π and hydrogen-bonding interactions. The polyaromatic cavity stabilizes hydrolyzable cyclic di(lactic acid) and captures tetra(lactic acid) preferentially from a mixture of oligo(lactic acid)s even in water.

Crystallization Induced Self-Assembly: A Strategy to Achieve Ultra-Small Domain Sizes

Achieving self-assembled nanostructures with ultra-small feature sizes (e. g., below 5 nm) is an important prerequisite for the development of block copolymer lithography. In this work, the preparation and self-assembly of a series of giant molecules composed of vinyl polyhedral oligomeric silsesquioxane (VPOSS) tethered with monodispersed oligo(L-lactide) chains are presented. Small-angle X-ray scattering (SAXS) and transmission electron microscopy (TEM) results demonstrate that ultra-small domain sizes (down to 3 nm) of phase separated lamellar morphology are achieved in bulk, driven by the strong tendency and fast kinetics for crystallization of VPOSS moieties. Moreover, upon gamma ray radiation, VPOSS cages in the lamellar structure can be crosslinked via polymerization of the vinyl groups. After pyrolysis at high temperature, ultra-thin two-dimensional nano-silica sheets can be obtained.

Synthesis and characterization of well-defined l-lactic acid-caprolactone co-oligomers and their rhenium (I) and technetium(I) conjugates

Staring from l-lactide and ε-caprolactone, the corresponding lactic-caprolactone cooligomer with hydroxyl and carboxylic acid groups were synthesized. These oligomers were connected with chelating groups through a long chain tether, ready for transition metal binding. Coordination of organometallic rhenium(I) and technetium(I) complexes generated the conjugates in high yield and short time, satisfying the requirements for short-lived radiopharmaceuticals in clinical applications. A reasonable pharmacophore model has been established to guide the design of well-defined lactic acid oligomer for nuclear medicine.