107938-31-8Relevant articles and documents
Synthesis Of Highly Functionalized Homochiral Azetidines And Azetidine-2-Carboxylic Esters
Dureault, Annie,Portal, Martine,Carreaux, Francois,Depezay, Jean Claude
, p. 4201 - 4210 (2007/10/02)
Homochiral (2S,3S)-3-benzyloxy-2-formyl-azetidines 2, (2S,3S)-3-benzyloxy-2-carbomethoxy-azetidines 3 and the highly strained (2S)-N-p-methoxyphenyl-2-silyloxymethyl-3-azetidinone 4 were successfully synthesized starting from diethyl-L-tartrate.The suitably functionalized azetidine ring is formed in a single synthetic operation with minimum protecting group chemistry.Key Words: Polyhydroxylated azetidines, 2-carbomethoxy-3-hydroxy-azetidines, 2-hydroxymethyl-3-azetidinone