107967-08-8

Upstream product

• 88-72-2 1-methyl-2-nitrobenzene 
• 107967-05-5 [1-(4-Methoxyphenyl)-2-(2-nitrophenyl)ethyl]-propanedioic acid,dimethyl ester 
• 107967-06-6 <2-(2-aminophenyl)-1-(4-methoxyphenyl)ethyl>propanedioic acid, dimethyl ester 
• 7443-25-6 dimethyl 2-(4-methoxybenzylidene)malonate 
• 129151-89-9 1,3,4,5-tetrahydro-3-(methoxycarbonyl)-4-(4-methoxyphenyl)-2H-1-benzazepin-2-one 

Downstream Products

• 129151-95-7 Acetic acid (3S,4R)-1-(2-dimethylamino-ethyl)-4-(4-methoxy-phenyl)-2-oxo-2,3,4,5-tetrahydro-1H-benzo[b]azepin-3-yl ester 
• 107967-13-5 (3S,4R)-1-(2-Dimethylamino-ethyl)-3-hydroxy-4-(4-methoxy-phenyl)-1,3,4,5-tetrahydro-benzo[b]azepin-2-one 
• 129151-92-4 trans-1,3,4,5-tetrahydro-3-hydroxy-4-(4-methoxyphenyl)-2H-1-benzazepin-2-one 
• 129151-91-3 cis-1,3,4,5-tetrahydro-3-hydroxy-4-(methoxyphenyl)-2H-1-benzazepin-2-one 

Relevant academic research and scientific papers

Benzazepinone calcium channel blockers. 4. Structure-activity overview and intracellular binding site

We have synthesized a series of benzazepinones (2) in order to determine the structure-activity relationships (SAR) for calcium channel blockers related to diltiazem. A prerequisite for calcium channel blocking activity in vitro and in vivo is the presenc