107970-42-3

Upstream product

• 18303-04-3 N-[(tert-butoxy)carbonyl]-4-methylbenzenesulfonamide 
• 309947-66-8 tert-butyl N-hex-5-ynyl-N-(p-tolylsulfonyl)carbamate 
• 928-90-5 5-hexyl-1-ol 
• 105678-98-6 hepta-5,6-dienal oxime 
• 107993-90-8 hepta-5,6-diene-1-amine 
• 98-59-9 p-toluenesulfonyl chloride 

Downstream Products

• 107970-32-1 methyl 2-acrylate 
• 107970-35-4 methyl 2-<1-methoxy-5-(p-tolylsulfonamido)pentyl>acrylate 
• 107970-36-5 methyl 2-(chloromethyl)-7-(p-tolylsulfonamido)hept-2-enoate 
• 107970-36-5 (Z)-2-Chloromethyl-7-(toluene-4-sulfonylamino)-hept-2-enoic acid methyl ester 
• 132937-98-5 (E)-7-iodo-1-(p-tolylsulfonyl)-1,2,3,4,5,8-hexahydro-1H-azocine 
• 132928-10-0 (Z,Z)-3,11-diiodo-N,N-bis(p-tolylsulfonyl)-1,9-diazacyclohexadeca-3,11-diene 
• 220384-49-6 (2R)-2-vinylpiperidine-1-carboxylic acid tert-butyl ester 
• 3197-44-2 (2R)-piperidin-2-ylmethanol 

Relevant academic research and scientific papers

Direct Intramolecular Aminoboration of Allenes

Direct intramolecular aminoboration of sulfonamidoallenes was realized using BCl3 as a boron source. The reactions benefited from the interaction between BCl3 and sulfonamides and provided a variety of borylvinyl heterocycles in good isolated yields. When chiral substrates were involved in the reactions, high stereoselectivity was observed, as can be ascertained by single-crystal X-ray diffraction experiments. Derivatization of the thus-obtained borylvinyl compounds proceeded readily, and different functionalities could be obtained via oxidation, halogenation, and Suzuki coupling reactions.

Rhodium-Catalyzed Asymmetric Intramolecular Hydroamination of Allenes

The rhodium-catalyzed asymmetric intramolecular hydroamination of sulfonyl amides with terminal allenes is reported. It provides selective access to 5- and 6-membered N-heterocycles, scaffolds found in a large range of different bioactive compounds. Moreover, gram scale reactions, as well as the application of suitable product transformations to natural products and key intermediates thereof are demonstrated.

Allene-based Electrophile-mediated Cyclisations: Efficient Synthesis of Medium Ring Azacycles

While AgI- and PdII-based electrophiles have limited application in cyclisation of allenic amines leading to 7-membered and larger azacycles, these rings may be obtained using iodine as the electrophilic trigger.Iodination of the N-b

Electrophile-mediated Cyclisations involving the Allene ?-System. Stereoselectivity and Synthetic Utility of PdII-Catalysed Heteroatom Cyclisation Reactions. X-Ray Molecular Structure of Methyl 2-

PdII-mediated cyclisation and methoxycarbonylation of the phenyl-substituted allenic sulfonamides 4, 5 and 6 gave the corresponding N-sulfonyl 2,3-, 2,4- and 2,5-disubstituted pyrrolidines 9, 10 and 11, respectively.With the exception of compou