108-09-8

Basic information

• Product Name: 1,3-Dimethylbutylamine
• Synonyms: (±)-4-Methyl-2-Pentanamine;1,3-Dimethylbutanamine;1,3-Dimethylbutylamin;1,3-dimethyl-butylamin;1-butanamine,1,3-dimethyl-;2-Pentanamine,4-methyl-;4-Methyl-2-aminopentan;4-Methyl-2-aminopentane
• CAS NO: 108-09-8
• Molecular Formula: C₆H₁₅N
• Molecular Weight: 101.19
• EINECS: 203-549-6
• Product Categories: Amines;C2 to C6;Nitrogen Compounds
• Mol File: 108-09-8.mol
• Article Data: 16

Chemical Properties

• Melting Point: -40.7°C (estimate)
• Boiling Point: 108-110 °C(lit.)
• Flash Point: 55 °F
• Appearance: Clear colorless/Liquid
• Density: 0.717 g/mL at 25 °C(lit.)
• Vapor Pressure: 25.9mmHg at 25°C
• Refractive Index: n20/D 1.4085(lit.)
• Storage Temp.: Flammables area
• PKA: 11.07±0.42(Predicted)
• CAS DataBase Reference: 1,3-Dimethylbutylamine(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3-Dimethylbutylamine(108-09-8)
• EPA Substance Registry System: 1,3-Dimethylbutylamine(108-09-8)

Safety Data

• Hazard Codes: F,C
• Statements: 11-22-34-20/21/22
• Safety Statements: 16-26-36/37/39-45
• RIDADR: UN 2379 3/PG 2
• WGK Germany: 3
• RTECS: EO4460000
• HazardClass: 3.1
• PackingGroup: II
• Hazardous Substances Data: 108-09-8(Hazardous Substances Data)

Usage

Chemical Properties

CLEAR COLOURLESS LIQUID

Uses

1,3-Dimethylbutylamine has been used to study the application of unfunctionized polymethacrylate resin (TSKgel G3000PWXL) as a stationary phase in liquid chromatography with UV detection.

General Description

A liquid with a fishlike odor. Less dense than water. Flash point 39 - 55°F. Vapors heavier than air. May be toxic by ingestion, inhalation and skin absorption.

Air & Water Reactions

Highly flammable. Slightly soluble in water. May be air sensitive.

Reactivity Profile

1,3-Dimethylbutylamine neutralizes acids in exothermic reactions to form salts plus water. May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen may be generated in combination with strong reducing agents, such as hydrides.

Health Hazard

May cause toxic effects if inhaled or ingested/swallowed. Contact with substance may cause severe burns to skin and eyes. Fire will produce irritating, corrosive and/or toxic gases. Vapors may cause dizziness or suffocation. Runoff from fire control or dilution water may cause pollution.

Fire Hazard

Flammable/combustible material. May be ignited by heat, sparks or flames. Vapors may form explosive mixtures with air. Vapors may travel to source of ignition and flash back. Most vapors are heavier than air. They will spread along ground and collect in low or confined areas (sewers, basements, tanks). Vapor explosion hazard indoors, outdoors or in sewers. Runoff to sewer may create fire or explosion hazard. Containers may explode when heated. Many liquids are lighter than water.

Safety Profile

Poison by intravenous route. Moderately toxic by ingestion and skin contact. Mildly toxic by inhalation. A dangerous fire and explosion hazard when exposed to heat or flame; can react vigorously with oxidizing materials. To fight fire, use foam, CO2 dry chemical. When heated to decomposition it emits toxic fumes of NOx See also MINES.

InChI:InChI=1/C6H15N/c1-5(2)4-6(3)7/h5-6H,4,7H2,1-3H3/p+1/t6-/m1/s1

Upstream product

• 2158-24-9 4-methyl-pent-3-en-2-one oxime 
• 108-10-1 4-methyl-2-pentanone 
• 141-79-7 4-methyl-pent-3-en-2-one 
• 7664-41-7 ammonia 
• 53867-52-0 bis-(1,3-dimethyl-butylidene)-hydrazine 
• 64-17-5 ethanol 
• 26842-43-3 2-amino-2,4-dimethylpentanonitrile 
• 7533-40-6 2-amino-4-methyl-1-pentanol 
• 7533-40-6 (S)-2-amino-4-methylpentan-1-ol 
• 75240-54-9 N-(4-methylpentan-2-yl)formamide 
• 100-46-9 benzylamine 
• 1258934-39-2 N-(4-methylpentan-2-yl)pyrimidine-2-sulfonamide 
• 68-11-1 mercaptoacetic acid 
• 105-44-2 4-methyl-pentan-2-one oxime 

Downstream Products

• 42966-64-3 N-ethyl-1,3-dimethylbutylamine 
• 42966-66-5 cyclohexyl-(1,3-dimethyl-butyl)-amine 
• 95945-86-1 (1,3-dimethyl-butyl)-[1-methyl-3-(2,6,6-trimethyl-cyclohex-1-enyl)-propyl]-amine 
• 40487-41-0 (1,3-Dimethyl-butyl)-(3,4-dimethyl-2,6-dinitro-phenyl)-amine 
• 40318-81-8 4-chloro-2,6-dinitro-N-(1,3-dimethylbutyl)-m-toluidine 
• 67330-79-4 1-(2,6-Diethyl-4-methyl-phenyl)-3-(1,3-dimethyl-butyl)-thiourea 
• 38008-69-4 (1,3-Dimethyl-butyl)-carbamic acid 3-methylsulfanylcarbonylamino-phenyl ester 
• 32781-26-3 (1,3-dimethyl-butyl)-(1,3-dimethyl-butyliden)-amine 
• 30121-94-9 4-{[(E)-1,3-Dimethyl-butylimino]-methyl}-phenol 
• 30121-92-7 4-{[(E)-1,3-Dimethyl-butylimino]-methyl}-2-methoxy-phenol 
• 78537-08-3 (R,S)-N-(tert-butyloxycarbonyl)-L-tyrosyl-D-alanylglycine 1,3-dimethylbutyl amide 
• 78537-10-7 (R,S)-N-(tert-butyloxycarbonyl)-L-tyrosyl-D-methionylglycine 1,3-dimethylbutyl amide 
• 108-10-1 4-methyl-2-pentanone 
• 1041850-75-2 (1,3-dimethylbutyl)-{4-[4-(4-fluorophenyl)-2-methylsulfanyl-1H-imidazol-5-yl]pyridin-2-yl}amine 

Related news

Identification and quantification of 1,3-Dimethylbutylamine (cas 108-09-8) (DMBA) from Camellia sinensis tea leaves and dietary supplements08/19/2019

1,3-dimethylbutylamine (DMBA), is a CNS stimulant, which has recently been identified in multiple dietary supplements and sometimes labeled as a natural constituent of Pouchung tea. DMBA is an homologue of 1,3-dimethylamylamine (DMAA) which the US Food and Drug Administration has attempted to re...detailed

Relevant articles and documents

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Ambient-Temperature Synthesis of Primary Amines via Reductive Amination of Carbonyl Compounds

Efficient synthesis of primary amines via low-temperature reductive amination of carbonyl compounds using NH3 and H2 as the nitrogen and hydrogen resources is highly desired and challenging in the chemistry community. Herein, we employed naturally occurring phytic acid as a renewable precursor to fabricate titanium phosphate (TiP)-supported Ru nanocatalysts with different reduction degrees of RuO2 (Ru/TiP-x, x represents the reduction temperature) by combining ball milling and molten-salt processes. Very interestingly, the obtained Ru/TiP-100 had good catalytic performance for the reductive amination of carbonyl compounds at ambient temperature, resulting from the synergistic cooperation of the support (TiP) and the Ru/RuO2 with a suitable proportion of Ru0 (52%). Various carbonyl compounds could be efficiently converted into the corresponding primary amines with high yields. More importantly, the conversion of other substrates with reducible groups could also be achieved at ambient temperature. Detailed investigations indicated that the partially reduced Ru and the support (TiP) were indispensable. The high activity and selectivity of Ru/TiP-100 catalyst originates from the relatively high acidity and the suitable electron density of metallic Ru0.

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