108014-73-9

Basic information

• Product Name: 3-chloro-9-phenoxy-acridine
• CAS NO: 108014-73-9
• Molecular Weight: 305.763
• Mol File: 108014-73-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-chloro-9-phenoxy-acridine(CAS DataBase Reference)
• NIST Chemistry Reference: 3-chloro-9-phenoxy-acridine(108014-73-9)
• EPA Substance Registry System: 3-chloro-9-phenoxy-acridine(108014-73-9)

Safety Data

• Hazardous Substances Data: 108014-73-9(Hazardous Substances Data)

Upstream product

• 35547-70-7 3,9-dichloroacridine 
• 108-95-2 phenol 

Downstream Products

• 58658-41-6 3-chloro-10-methylacridin-9(10H)-one 
• 3407-98-5 5-Amino-2-chloroacridin 

Relevant articles and documents

Synthesis of monomeric and dimeric acridine compounds as potential therapeutics in Alzheimer and prion diseases

Starting from substituted 9-chloroacridines, a series of quinacrine and spacered dimeric acridine compounds was prepared. Their ability to interrupt the protein association of prion- and Alzheimer-specific proteins and Ab peptides was explored using a fast screening system based on FACS analysis. The bis-acridines displayed a higher activity than the corresponding monomers. Among these derivatives, best results were obtained with the 2,4-dimethoxy-6-nitro compound 7h for Aβ-peptides and the 2-methoxy-6-nitro compound 7f for PrP.