108019-30-3

Basic information

• Product Name: Benzenepentanoic acid, a-(acetylamino)-
• CAS NO: 108019-30-3
• Molecular Formula: C13H17NO3
• Molecular Weight: 235.283
• Mol File: 108019-30-3.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: Benzenepentanoic acid, a-(acetylamino)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenepentanoic acid, a-(acetylamino)-(108019-30-3)
• EPA Substance Registry System: Benzenepentanoic acid, a-(acetylamino)-(108019-30-3)

Safety Data

• Hazardous Substances Data: 108019-30-3(Hazardous Substances Data)

Upstream product

• 4392-24-9 Cinnamyl bromide 
• 101782-54-1 Acetamino-cinnamyl-malonsaeure-diethylester 
• 637-59-2 1-Bromo-3-phenylpropane 
• 52161-73-6 2-acetylamino-2-(3-phenyl-propyl)malonic acid diethyl ester 
• 108246-15-7 (+/-)-4-Acetamino-1-phenyl-penten-⁽¹⁾-saeure-⁽⁵⁾ 

Downstream Products

• 34993-02-7 2-(R)-amino-5-phenylpentanoic acid 
• 36061-08-2 (2R)-2-amino-5-phenylpentanoic acid 
• 156130-68-6 2-(tert-butoxycarbonylamino)-5-phenyl-D-pentanoic acid 
• 416856-10-5 [1-(1-{[5-(4-chloro-phenyl)-3,3-dimethyl-1,1-dioxo-2,3-dihydro-1H-1λ⁶-isothiazol-4-ylmethyl]-ethyl-carbamoyl}-4-phenyl-butylcarbamoyl)-1-methyl-ethyl]-carbamic acid tert-butyl ester 
• 206360-08-9 2-tert-butoxycarbonylamino-5-phenyl-pentanoic acid ethyl ester 
• 62777-26-8 D-N-acetyl-2-amino-5-phenylpentanoic acid 
• 106270-07-9 2-methyl-4-(3-phenyl-propyl)-4H-oxazol-5-one 

Relevant articles and documents

Structure activity studies of the serine-AIB dipeptide domain in 2,3-dihydroisothiazole based growth hormone secretagogues

A series of growth hormone secretagogues (GHSs) based on 2,3-dihydroisothiazole has been synthesized in the search for a potential treatment of growth hormone deficiency or frailty in the elderly. This paper describes the evaluation of the SAR of the benzyl-d-Ser-aminoisobutyric acid dipeptide fragment. Introduction of substituents in the peptide backbone and in the phenyl ring has been investigated, as well as replacements for the benzyl group and for the AIB residue. A number of modifications resulted in enhanced potency over the parent benzyl-d-Ser-AIB derivative.

STEREOSELECTIVE PROCESS FOR THE SYNTHESIS OF (D)-2-AMINO-5-PHENYLPENTANOIC OR ALKYL ESTER THEREOF

The present invention provides a process for preparing a compound of formula (I); wherein R is a C1-C6 alkyl; or a salt thereof; comprising:(c) hydrolyzing (D,L)-N-acetyl-2-amino-5-phenylpentanoic acid with a suitable base in the pre

Substituted acetamidomalonic esters and DL-2-acetamido acids as antitumor agents.

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