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108087-84-9

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108087-84-9 Usage

General Description

N-(4-Ethoxyphenyl)maleamic acid is a chemical compound that belongs to the class of maleamic acids, which are derivative of maleic acid. It is a white to off-white solid with a molecular formula C12H11NO4. The compound is used in the synthesis of various organic compounds and can act as a crosslinking agent in polymer chemistry. N-(4-Ethoxyphenyl)maleamic acid has potential applications in pharmaceuticals, agrochemicals, and material science. It is also utilized in research studies and as a building block in organic synthesis.

Check Digit Verification of cas no

The CAS Registry Mumber 108087-84-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,8,0,8 and 7 respectively; the second part has 2 digits, 8 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 108087-84:
(8*1)+(7*0)+(6*8)+(5*0)+(4*8)+(3*7)+(2*8)+(1*4)=129
129 % 10 = 9
So 108087-84-9 is a valid CAS Registry Number.
InChI:InChI=1/C12H13NO4/c1-2-17-10-5-3-9(4-6-10)13-11(14)7-8-12(15)16/h3-8H,2H2,1H3,(H,13,14)(H,15,16)/b8-7-

108087-84-9 Well-known Company Product Price

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  • Alfa Aesar

  • (B25024)  N-(4-Ethoxyphenyl)maleamic acid, 97%   

  • 108087-84-9

  • 5g

  • 440.0CNY

  • Detail
  • Alfa Aesar

  • (B25024)  N-(4-Ethoxyphenyl)maleamic acid, 97%   

  • 108087-84-9

  • 25g

  • 1611.0CNY

  • Detail
  • Alfa Aesar

  • (B25024)  N-(4-Ethoxyphenyl)maleamic acid, 97%   

  • 108087-84-9

  • 100g

  • 4754.0CNY

  • Detail

108087-84-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 11, 2017

Revision Date: Aug 11, 2017

1.Identification

1.1 GHS Product identifier

Product name N-(4-ETHOXYPHENYL)MALEAMIC ACID

1.2 Other means of identification

Product number -
Other names Maleinsaeure-mono-p-ethoxy-anilid

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
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More Details:108087-84-9 SDS

108087-84-9Relevant articles and documents

The discovery, design and synthesis of potent agonists of adenylyl cyclase type 2 by virtual screening combining biological evaluation

Li, Shanshan,Song, Gao,Wang, Liang-Liang,Weng, Zhiying,Xu, Guowei,Yang, Weimin,Yang, Yanming,Yang, Yaqing,Zhang, Jiajun,Zuo, Zhili

supporting information, (2020/02/27)

Adenylate cyclases (ACs), play a critical role in the conversion of adenosine triphosphate (ATP) into the second messenger cyclic adenosine monophosphate (cAMP). Studies have indicated that adenylyl cyclase type 2 (AC2) is potential drug target for many diseases, however, up to now, there is no AC2-selective agonist reported. In this research, docking-based virtual screening with the combination of cell-based biological assays have been performed for discovering novel potent and selective AC2 agonists. Virtual screening disclosed a novel hit compound 8 as an AC2 agonist with EC50 value of 8.10 μM on recombinant human hAC2 + HEK293 cells. The SAR (structure activity relationship) based on the derivatives of compound 8 was further explored on recombinant AC2 cells and compound 73 was found to be the most active agonist with the EC50 of 90 nM, which is 160-fold more potent than the reported agonist Forskolin and could selectively activate AC2 to inhibit the expression of Interleukin-6. The discovery of a new class of AC2-selective agonists would provide a novel chemical probe to study the physiological function of AC2.

Solvent-free and room temperature visible light-induced C-H activation: CdS as a highly efficient photo-induced reusable nano-catalyst for the C-H functionalization cyclization of: T -amines and C-C double and triple bonds

Firoozi, Somayeh,Hosseini-Sarvari, Mona,Koohgard, Mehdi

supporting information, p. 5540 - 5549 (2019/01/03)

Nano-sized CdS was successfully prepared, fully characterized and applied as a highly efficient reusable photocatalyst for the synthesis of pyrrolo[3,4-c]quinolone and pyrrolo[2,1-a]isoquinoline-8-carboxylate derivatives through a condensation reaction of N,N-dimethylanilines or alkyl 2-(3,4-dihydroisoquinolin-2(1H)-yl)acetates with maleimides via a C-H activation approach under benign and eco-friendly conditions at room temperature without using any solvent and oxidant under visible light irradiation. Besides, the prepared photocatalyst has been successfully applied for the condensation reaction of N,N-dimethylanilines with alkyl but-2-ynedioates or phenyl acetylenes for the synthesis of novel 1,2-dihydroquinoline-3,4-dicarboxylate and aryl-1,2-dihydroquinoline derivatives for the first time. Using this method, all favourable products were obtained in good yields and relatively short reaction times under benign conditions with the application of visible light irradiation, a renewable energy source. The catalyst was easily recovered and reused several times without any loss of its activity.

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