4345-85-1

Basic information

• Product Name: 1-(4-ethoxyphenyl)-3-phenylurea
• CAS NO: 4345-85-1
• Molecular Formula: C₁₅H₁₆N₂O₂
• Molecular Weight: 256.2997
• Mol File: 4345-85-1.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 320.3°C at 760 mmHg
• Flash Point: 147.5°C
• Density: 1.218g/cm³
• Vapor Pressure: 0.000321mmHg at 25°C
• Refractive Index: 1.646
• CAS DataBase Reference: 1-(4-ethoxyphenyl)-3-phenylurea(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(4-ethoxyphenyl)-3-phenylurea(4345-85-1)
• EPA Substance Registry System: 1-(4-ethoxyphenyl)-3-phenylurea(4345-85-1)

Safety Data

• Hazardous Substances Data: 4345-85-1(Hazardous Substances Data)

Usage

Molecular weight

269.3 g/mol

Usage

Herbicide

Function

Inhibits photosynthesis in plants

Effect on plants

Growth inhibition and eventual death

Effective against

Broadleaf weeds and grasses

Applications

Agricultural and horticultural

Safety concerns

Toxic to humans and non-target organisms if not used properly

Upstream product

• 103-71-9 phenyl isocyanate 
• 156-43-4 4-Ethoxyaniline 
• 108087-84-9 N-(4-ethoxy-phenyl)-maleamic acid 
• 108-88-3 toluene 
• 740-80-7 N,N'-bis-(4-ethoxy-phenyl)-urea 
• 62-53-3 aniline 
• 32459-62-4 4-ethoxyphenyl isocyanate 
• 1756-43-0 N-(4-ethoxyphenyl)-N'-phenylthiourea 
• 87597-54-4 3-(4-Ethoxy-phenyl)-4-oxo-3,4-dihydro-imidazo[5,1-d][1,2,3,5]tetrazine-8-carboxylic acid amide 
• 7647-01-0 hydrogenchloride 
• 64-17-5 ethanol 
• 860574-53-4 1-(4-ethoxy-phenyl)-3-phenyl-triazene-1-carboxylic acid anilide 
• 64-10-8 phenyl carbamate 
• 699-08-1 1-ethoxy-4-iodobenzene 

Downstream Products

• 130632-36-9 2-Diethylamino-1-(4-ethoxy-phenyl)-3-phenyl-[1,3,2]diazaphosphetidin-4-one 

Relevant articles and documents

Palladium-Catalyzed Aerobic Oxidative Carbonylation of Amines Enables the Synthesis of Unsymmetrical N,N′-Disubstituted Ureas

A ligand-free palladium-catalyzed aerobic oxidative carbonylation of amines for the synthesis of ureas, particular unsymmetrically N,N′-disubstituted ureas, which cannot be accessed by any other palladium-catalyzed oxidative carbonylation of amines to date, is presented. An array of symmetrical and unsymmetrical ureas were straightforwardly synthesized by using inexpensive, readily available, stable, and safe amines with good to excellent yields under a pressure of 1 atm. This novel method employs oxygen as the sole oxidant and offers an attractive alternative to transition-metal-based oxidant systems.

An efficient and mild protocol for the synthesis of unsymmetrical ureas in the absence of catalyst and additives

A new practical method for the synthesis of unsymmetrical ureas was achieved by reaction of phenylurea with primary and secondary amines under neutral and mild condition in very good yields. The reaction took place in refluxing dioxane and does not require any catalyst or additives.

DIARYL UREAS AS CB1 ANTAGONISTS

Compounds of Formula I are provided. In which the variables are as described herein. Such compounds may be used to modulate CB1 activity in vivo or in vitro, and are particularly useful in the treatment of conditions responsive to CB1 modulation in humans, domesticated companion animals and livestock animals, including appetite disorders, obesity and addictive disorders. Pharmaceutical compositions and methods for using them to treat such disorders are provided, as are methods for using such ligands for receptor localization studies and various in vitro assays.