108142-72-9

Basic information

• Product Name: (S)-3-<3-Acetyl-4-(2,2-dimethyl-1,3-dioxolan-4-yl-methoxy)-phenyl>-1,1-diethylharnstoff
• Synonyms: (S)-3-<3-Acetyl-4-(2,2-dimethyl-1,3-dioxolan-4-yl-methoxy)-phenyl>-1,1-diethylharnstoff
• CAS NO: 108142-72-9
• Molecular Weight: 364.442
• Mol File: 108142-72-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (S)-3-<3-Acetyl-4-(2,2-dimethyl-1,3-dioxolan-4-yl-methoxy)-phenyl>-1,1-diethylharnstoff(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-3-<3-Acetyl-4-(2,2-dimethyl-1,3-dioxolan-4-yl-methoxy)-phenyl>-1,1-diethylharnstoff(108142-72-9)
• EPA Substance Registry System: (S)-3-<3-Acetyl-4-(2,2-dimethyl-1,3-dioxolan-4-yl-methoxy)-phenyl>-1,1-diethylharnstoff(108142-72-9)

Safety Data

• Hazardous Substances Data: 108142-72-9(Hazardous Substances Data)

Upstream product

• 79881-89-3 3-(3-Acetyl-4-hydroxy-phenyl)-1,1-diethylharnstoff 
• 23788-74-1 (R)-2,2-dimethyl-1,3-dioxolane-4-ylmethyl p-toluenesulfonate 

Downstream Products

• 108142-75-2 (R)-3-<3-Acetyl-4-(oxolanyl-methoxy)-phenyl>-1,1-diethylharnstoff 
• 108142-74-1 (S)-3-<3-Acetyl-4-(2-hydroxy-3-tosyloxy-propoxy)-phenyl>-1,1-diethylharnstoff 
• 108142-73-0 (R)-3-<3-Acetyl-4-(2,3-dihydroxy-propoxy)-phenyl>-1,1-diethylharnstoff 

Relevant articles and documents

Absolute configuration and enantiomeric purity of celiprolol

The absolute configuration of (+)-celiprolol ([α]D = +6.3° in CHCl3) was established by a 9-step synthesis via the (+) (R)-acetonide of (R)-glyceraldehyde. This result was confirmed by the Cupra-A CD-spectra of the isopropyl and hydroxyl analogs. The enantiomeric purity was determined by NMR analysis of the diastereomeric amide esters obtained by reaction of celiprolol with 2 mol of α-methoxy-α-trifluormethylphenylacetic acid chloride (Mosher's reagent).