108239-92-5Relevant academic research and scientific papers
Amine-effected cyclization of chalcone dihalides to aurones
Donnelly, John A.,Emerson, Geraldine M.
, p. 7227 - 7236 (2007/10/02)
The possibility of employing the amine-catalysed cyclization of αβ-dibromodihydrochalcones and α-bromochalcones as a general synthesis of aurones was studied using cyclohexylamine and the most representative member of each class of these αβ-disubstituted ketones and α-halogeno chalcones. Overall yields of heterocyclic products were generally poor except from 4′6′-dimethoxy- and 3-nitro-substituted chalcone systems; aurones were obtained in fair yield from the former and in excellent yield from the latter. 22′-Diacetoxychalcone dibromide and 22′-diacetoxy-α-bromochalcone cyclised to a 2-benzoylbenzofuran to the exclusion of the corresponding aurone and flavone.
Condensation Product of Salicylaldehyde and 2-Bromo-2'-hydroxyacetophenone: Revision of Structure
Joshi, U. K.,Paradkar, M. V.
, p. 378 - 379 (2007/10/02)
Reaction between salicylaldehyde and 2-bromo-2'-hydroxyacetophenone (1) gives 2-(2-hydroxybenzylidene)coumaran-3-one (5) rather than 2-(2-hydroxybenzoyl)benzofuran (2) as reported in a patented literature.
Synthesis of 4-(2-Benzofuranyl)coumarins
Deshpande, A. R.,Joshi, U. K.,Paradkar, M. V.
, p. 524 - 526 (2007/10/02)
4-(2-Benzofuranyl)coumarins (3) have been synthesized by two routes, one involving Pechmann condensation of benzofuranpropionic acid-β-oxo-ethyl ester with phenols and the other involving Wittig reaction on 2-(2-hydroxybenzoyl)benzofuran using Ph3P=CHCOOE
