108244-44-6

Basic information

• Product Name: 2-Chloro-6-isopropylnicotinonitrile
• Synonyms: 2-Chloro-6-isopropylnicotinonitrile
• CAS NO: 108244-44-6
• Molecular Formula: C9H9ClN2
• Molecular Weight: 180.63416
• Mol File: 108244-44-6.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 270.3±40.0 °C(Predicted)
• Appearance: /
• Density: 1.17±0.1 g/cm3(Predicted)
• PKA: -1.40±0.10(Predicted)
• CAS DataBase Reference: 2-Chloro-6-isopropylnicotinonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Chloro-6-isopropylnicotinonitrile(108244-44-6)
• EPA Substance Registry System: 2-Chloro-6-isopropylnicotinonitrile(108244-44-6)

Safety Data

• Hazard Codes: T
• Statements: 25
• Safety Statements: 45
• HazardClass: IRRITANT
• Hazardous Substances Data: 108244-44-6(Hazardous Substances Data)

Upstream product

• 6602-54-6 2-chloro-3-pyridinecarbonitrile 
• 79-31-2 isobutyric Acid 
• 5782-69-4 2-hydroxy-6-isopropyl-nicotinonitrile 
• 5782-69-4 6-isopropyl-2-oxo-1,2-dihydropyridine-3-carbonitrile 

Downstream Products

• 166331-65-3 2-chloro-6-isopropylnicotinic acid 
• 1033750-40-1 6-isopropylnicotinonitrile 

Relevant articles and documents

MODULATORS OF HSD17B13 AND METHODS OF USE THEREOF

The disclosure relates to compounds and pharmaceutical compositions capable of modulating the hydroxysteroid 17-beta dehydrogenase (HSD17B) family member proteins including inhibiting the HSD17B member proteins, e.g. HSD17B13. The disclosure further relates to methods of treating liver diseases, disorders, or conditions with the compounds and pharmaceutical compositions disclosed herein, in which the HSD17B family member protein plays a role.

OPTICALLY ACTIVE TETRAHYDRONAPHTHALENE DERIVATIVE

A compound represented by the following formula (I), a pharmacologically acceptable salt thereof or a hydrate thereof or a solvate thereof, which shows not only a C5a receptor antagonistic activity but also high activity in the biological availability, as