108249-43-0

Basic information

• Product Name: 3-BROMO-4-HYDROXY-5-METHOXY-BENZOIC ACID METHYL ESTER
• Synonyms: 3-BROMO-4-HYDROXY-5-METHOXY-BENZOIC ACID METHYL ESTER;RARECHEM AL BF 0099;Methyl 3-bromo-4-hydroxy-5-methoxybenzoate;Methyl 5-bromo-4-hydroxy-3-methoxybenzoate
• CAS NO: 108249-43-0
• Molecular Formula: C₉H₉BrO₄
• Molecular Weight: 261.07
• Mol File: 108249-43-0.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• Storage Temp.: Room temperature.
• CAS DataBase Reference: 3-BROMO-4-HYDROXY-5-METHOXY-BENZOIC ACID METHYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: 3-BROMO-4-HYDROXY-5-METHOXY-BENZOIC ACID METHYL ESTER(108249-43-0)
• EPA Substance Registry System: 3-BROMO-4-HYDROXY-5-METHOXY-BENZOIC ACID METHYL ESTER(108249-43-0)

Safety Data

• Hazardous Substances Data: 108249-43-0(Hazardous Substances Data)

Usage

General Description

3-BROMO-4-HYDROXY-5-METHOXY-BENZOIC ACID METHYL ESTER is a chemical compound with the molecular formula C9H9BrO4. It is a methyl ester derivative of 3-bromo-4-hydroxy-5-methoxy-benzoic acid, which is commonly found in plants as a natural product. 3-BROMO-4-HYDROXY-5-METHOXY-BENZOIC ACID METHYL ESTER is commonly used in organic synthesis and pharmaceutical research as a building block or intermediate. It has potential applications in the development of new drugs or agrochemicals due to its unique structure and properties. Additionally, it can also be utilized in various chemical reactions as a reagent or catalyst.

Upstream product

• 121-34-6 3-methoxy-4-hydroxybenzoic acid 
• 3943-74-6 4-hydroxy-3-methoxybenzoic acid methyl ester 
• 67-56-1 methanol 
• 6324-52-3 3-bromo-4-hydroxy-5-methoxybenzoic acid 

Downstream Products

• 55182-57-5 2-Bromo-4-isopropylidene-6-methoxy-cyclohexa-2,5-dienone 
• 175668-18-5 4-Acetoxy-3-methoxy-5-((2E,6E)-3,7,11-trimethyl-dodeca-2,6,10-trienyl)-benzoic acid methyl ester 
• 23523-94-6 1-methoxy-3-methoxycarbonyl-9H-carbazole 
• 175668-15-2 4-Acetoxy-3-bromo-5-methoxy-benzoic acid methyl ester 

Relevant articles and documents

Bacterial Catabolism of Biphenyls: Synthesis and Evaluation of Analogues

A series of alkylated 2,3-dihydroxybiphenyls has been prepared on the gram scale by using an effective Directed ortho Metalation–Suzuki–Miyaura cross-coupling strategy. These compounds have been used to investigate the substrate specificity of the meta-cl

Double N-arylation of primary amines: Carbazole synthesis from 2,2′-biphenyldiols

(Chemical Equation Presented) The double N-arylation of primary amines with 2,2′-biphenylylene ditriflates was investigated for the synthesis of multisubstituted carbazoles. Palladium complexes supported by 2-dicyclohexylphosphino-2′-methylbiphenyl or Xantphos [4,5- bis(diphenylphosphino)-9,9-dimethylxanthene] were found to be efficient catalysts for the reaction. The catalysts allow the use of anilines with an electron-donating or electron-withdrawing substituent and multisubstituted 2,2′-biphenylylene ditriflates as substrates. Ammonia equivalents, such as O-tert-butyl carbamate, are also employable as a nitrogen source to give the N-protected carbazoles which can easily give the corresponding N-unsubstituted carbazoles after deprotection. By using this methodology, a carbazole alkaloid, mukonine, is synthesized in 40% yield for five steps, in comparable efficiency to the recent precedents.