108279-08-9Relevant academic research and scientific papers
Development of peptide 3D structure mimetics: Rational design of novel peptoid cholecystokinin receptor antagonists
Low,Black,Broughton,Buck,Davies,Dunstone,Hull,Kalindjian,McDonald,Pether,Shankley,Steel
, p. 3505 - 3517 (2007/10/03)
The two hormones cholecystokinin and gastrin share the same C-terminal sequence of amino acids, namely Gly29-Trp30-Met31-Asp32-Phe33-NH2. Nevertheless, this congruence has not precluded usi
Studies on inhibition of enzymatic arginyltransfer reaction
Takao, Koichi,Igarashi, Toshihisa,Ogiso, Hironao,Ugata, Kazuya,Shirahata, Akira,Samejima, Keijiro
, p. 1169 - 1172 (2007/10/03)
Synthetic polyamines and various derivatives of aspartic acid and glutamic acid were examined in vitro for their inhibitory activity on arginyl-tRNA-protein transferase. All the polyamines tested showed non- specific activation or inhibition at 0.1 or 10
ANALOGUES OF THE CHOLECYSTOKININ C-TERMINAL TETRRAPEPTIDE
Hlavacek, Jan,Marcova, Renata,Maletinska, Lenka,Slaninova, Jirina
, p. 2511 - 2522 (2007/10/02)
Substituted phenylethyl amides and phenylethyl esters Va - Vj derived from the carboxyterminal tetrapeptide part of the cholecystokinin were synthesized and their biological properties assayed.In the original CCK tetrapeptide structure Trp-Met-Asp-Phe-NH2
Development of a Small RGD Peptide Fibrinogen Receptor Antagonist with Potent Antiaggregatory Activity in Vitro
Samanen, J.,Ali, F.,Romoff, T.,Calvo, R.,Sorenson, E.,et al.
, p. 3114 - 3125 (2007/10/02)
The development of potent antithrombotic agents from the fibrinogen platelet receptor binding sequences Fg-α 572-575 -Arg-Gly-Asp-Ser- and Fg-γ 400-411 -HHLGGAKQAGDV, believed to be a cryptic RGD-type sequence, is described.The tetrapeptide Ac-RGDS-NH2 it
