1083067-06-4

Basic information

• Product Name: 2-amino-7-(4-fluoro-phenyl)-4-methyl-7,8-dihydro-6H-quinazolin-5-one O-(2-dimethylamino-ethyl)-oxime
• Synonyms: 2-amino-7-(4-fluoro-phenyl)-4-methyl-7,8-dihydro-6H-quinazolin-5-one O-(2-dimethylamino-ethyl)-oxime
• CAS NO: 1083067-06-4
• Molecular Weight: 357.431
• Mol File: 1083067-06-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-amino-7-(4-fluoro-phenyl)-4-methyl-7,8-dihydro-6H-quinazolin-5-one O-(2-dimethylamino-ethyl)-oxime(CAS DataBase Reference)
• NIST Chemistry Reference: 2-amino-7-(4-fluoro-phenyl)-4-methyl-7,8-dihydro-6H-quinazolin-5-one O-(2-dimethylamino-ethyl)-oxime(1083067-06-4)
• EPA Substance Registry System: 2-amino-7-(4-fluoro-phenyl)-4-methyl-7,8-dihydro-6H-quinazolin-5-one O-(2-dimethylamino-ethyl)-oxime(1083067-06-4)

Safety Data

• Hazardous Substances Data: 1083067-06-4(Hazardous Substances Data)

Upstream product

• 1083067-14-4 C₁₈H₂₀FNO₂ 
• 945298-72-6 2-amino-7-(4-fluoro-phenyl)-4-methyl-7,8-dihydro-6H-quinazolin-5-one 
• 1083067-13-3 2-acetyl-5-(4-fluorophenyl)cyclohexane-1,3-dione 
• 1083066-89-0 2-amino-7-(4-fluoro-phenyl)-4-methyl-7,8-dihydro-6H-quinazolin-5-one oxime 
• 4584-46-7 (2-chloroethyl)dimethylamine hydrochloride 
• 55579-72-1 5-(4-fluoro-phenyl)-cyclohexane-1,3-dione 

Relevant articles and documents

QUINAZOLIN-OXIME DERIVATIVES AS HSP90 INHIBITORS

Compounds of general formula (I); or a stereoisomers, tautomers, pharmaceutically acceptable salts, or prodrugs thereof, wherein R1, R2, R3, R4, R5, R6, R8 and R9 are as defined herein, are useful for the treatment of diseases and conditions which are mediated by excessive or inappropriate Hsp90 activity such as cancers, viral infection and inflammatory diseases or conditions.