1083433-29-7Relevant academic research and scientific papers
Synthesis and Biological Evaluation of Cajaninstilbene Acid and Amorfrutins A and B as Inhibitors of the Pseudomonas aeruginosa Quorum Sensing System
Xu, Xing-Jun,Zeng, Ting,Huang, Zhi-Xing,Xu, Xiao-Fang,Lin, Jing,Chen, Wei-Min
, p. 2621 - 2629 (2018)
The quorum sensing (QS) system inhibitors of Pseudomonas aeruginosa are thought to attenuate bacterial pathogenicity and drug resistance by inhibiting biofilm formation and the production of virulence factors. In this study, a synthetic approach to the na
Unified total synthesis of amorfrutins A and C via the Claisen rearrangement
Fujita, Tadafumi,Kuwahara, Shigefumi,Ogura, Yusuke
, p. 1635 - 1641 (2019/08/20)
A concise, unified total synthesis of the two prenylated aromatic polyketides amorfrutins A and C, which exhibit various medicinally important biological profiles such as antimicrobial, PPAR? modulating and quorum sensing inhibitory activities, has been a
A wood swainsonine and its analog of chemical preparation method
-
, (2019/07/04)
The invention belongs to the field of synthetic wood swainsonine, discloses a wood swainsonine and its analog of chemical preparation method. The method in order to 2 - bromo - 4, 6 - dimethoxy formaldehyde and substituted styrene as the starting material, through the 6 step chemical synthesis for preparing [...] and its structural analogs, and through to the synthesis method is a simple conversion alkylation reagent or to adds the hydrogenation step can also be prepared to wood amino analog, the method has the steps brief, raw materials are cheap and easy to obtain, overall yield and the like. The method of the invention on the synthesis of cajan element analogs have universal applicability.
An efficient synthesis of bibenzylic oxygen heterocycles
Kumbhar, Virendra B.,Joseph, Augustine R.,Natu, Arun D.,Kusurkar, Radhika S.,Paradkar, Madhusudan V.
, p. 590 - 593 (2008/09/20)
The first total syntheses of naturally occurring 6-methoxy-4-(2- phenylethyl)benzofuran (1) and 2,2-dimethyl-7-methoxy-5-(2-phenylethyl)chroman (2) and the non-natural 7-methoxy-5-(2-phenylethyl)chromen-2-one (3) are described from 3,5-dimethoxyphenylacet
