108362-06-7Relevant academic research and scientific papers
Gold(III)-catalyzed synthesis of 2,5-disubstituted furans from substituted 5-methoxyhex-3-yn-2-ols—Mechanistic outlook
Behera, Sagarika,Bera, Nabakumar,Sarkar, Debayan
, p. 3090 - 3098 (2021)
Gold(III)-catalyzed activation of alkynes has been applied for the synthesis of 2,5-disubstituted furans from substituted 5-methoxy-hex-3-yn-2-ols. Mechanistically, the reaction proceeds via an allenyl carbocation intermediate followed by 5-endo-dig cyclization. The high-yielding, open-air, room temperature reaction conditions applied to synthesize a series of alkyl, aryl, and hetero aryl-substituted furans provide uniqueness to the strategy.
Dual Oxidation State Tandem Catalysis in the Palladium-Catalyzed Isomerization of Alkynyl Epoxides to Furans
Arroniz, Carlos,Chaubet, Guilhem,Anderson, Edward A.
, p. 8290 - 8295 (2018)
A two-catalyst system consisting of different oxidation states of palladium is described, which mediates the isomerization of alkynyl epoxides to furans. In a process termed dual oxidation state tandem catalysis , a multistep isomerization pathway is delineated in which the different metal oxidation states and ligands play independent mechanistic roles, but which, in combination, enable the use of milder reaction conditions and lower catalyst loadings than a single catalyst in isolation. In the present context, this rare example of a homobimetallic catalytic transformation provides a mild, scalable, and atom-efficient route for furan synthesis.
The Photochemistry of α,β-Acetylenic Ketones. II. Formation of Furan Derivatives
Nishio, Takehiko,Nakata, Hiroyuki,Omote, Yoshimori
, p. 1011 - 1013 (2007/10/02)
The phochemical reactions of α,β-acetylenic ketones have been examined.Irradiation of 1-p-substituted phenyl-2-propyn-1-ones 2-4 in primary alcohols gave 2,5-disubstituted furans 2a-4c.The formation of furans can be explained in terms of cyclization, foll
A NOVEL PALLADIUM-CATALYZED REARRANGEMENT OF ACETYLENIC KETONES TO FURANS
Sheng, Huaiyu,Lin, Shouyuan,Huang, Yaozeng
, p. 4893 - 4894 (2007/10/02)
A novel rearrangement of 1-aryl-4-alkyl-2-butyn-1-one in the presence of Pd(dba)2-PPh3 catalyst gave 2,4-substituted furans in moderate yields.
