108377-17-9Relevant academic research and scientific papers
Facile Conversion of Aldehydes into 1-Substituted 2-Chloro-3,3-difluoro-2-propen-1-ols with 1,1-Dibromo-1-chloro-2,2,2,-trifluoroethane/Magnesium Reagent
Fujita, Makoto,Hiyama, Tamejiro
, p. 3321 - 3322 (1988)
Aldehydes RCHO are converted in excellent yields into chlorodifluoroallyl alcohols RCH(OH)CCl=CF2 upon treatment with CClBr2CF3 and magnesium in tetrahydrofuran at 0 deg C.
Synthetic utility of HCFC-123 (2,2-dichloro-1,1,1-trifluoroethane): the reaction between HCFC-123 and aldehydes using zinc
Tamura, Masanori,Sekiya, Akira
, p. 119 - 122 (2007/10/02)
HCFC-123 (2,2-dichloro-1,1,1-trifluoroethane) reacted with zinc and aldehydes to afford predominantly either 1-substituted 2-chloro-3,3-difluoro-2-propen-1-ols or 1-substituted 2,2-dichloro-3,3,3-trifluoro-1-propanols.The reactions proceeded via 1,1-dichloro-2,2,2-trifluoroethylzinc chloride as an organozinc intermediate. - Keywords: 2,2-Dichloro-1,1,1-trifluoroethane; Reaction; Aldehydes; Zinc; 1,1-Dichloro-2,2,2-trifluoroethylzinc chloride
Efficient Carbonyl Addition of Polyfluorochloroethyl, -ethylidene, and -ethenyl Units by Means of 1,1,1-Trichloro-2,2,2-trifluoroethane and Zinc
Fujita, Makoto,Hiyama, Tamejiro
, p. 4377 - 4384 (2007/10/02)
Thermally stable zinc carbenoid CF3CCl2ZnCl was prepared from 1,1,1-trichloro-2,2,2-trifluoroethane and zinc powder in N,N-dimethylformamide and was allowed to add to carbonyls of aldehydes and α-keto esters in excellent yields to give 1-substituted 2,2-d
PRACTICAL WAYS FROM ALDEHYDES TO 2-CHLORO-1,1,1-TRIFLUORO-2-ALKENES AND 2-CHLORO-1,1-DIFLUORO-1-ALKEN-3-OLS
Fujita, Makoto,Hiyama, Tamejiro
, p. 3655 - 3658 (2007/10/02)
A reagent system CF3CCl3/Zn(>2 mol)/Ac2O transformed aldehydes to 2-chloro-1,1,1-trifluoro-2-alkenes exclusively, whereas CF3CCl3/Zn(>2 mol)/AlCl3(cat.) converted aldehydes into 2-chloro-1,1-difluoro-1-alken-3-ols.
