108499-38-3

Upstream product

• 2899-67-4 ethyl (benzylthio)acetate 
• 100-53-8 phenylmethanethiol 

Downstream Products

• 109950-15-4 2-benzylthio-1,3-propanediol 

Relevant academic research and scientific papers

Facile synthesis of 3-benzylsulfinyl- and 3-benzylsulfonyl-7- diethylaminocoumarins

The efficient synthesis of a 3-benzylsulfinylcoumarin and a 3-benzylsulfonylcoumarin starting from thiobenzyl alcohol using solvent-free Knoevenagel reaction as the key step is reported. Moreover, the molecular structure of 3-benzylsulfonyl-7-diethylamino

Synthesis, characterization and application of nano-sized Co 2CrO4 spinel catalyst for selective oxidation of sulfides to sulfoxides

The nano-sized Co2CrO4 spinel was produced for the first time by thermal decomposition of Cr-Co gel prepared by sol-gel method. It was shown that well-crystallized spinel structure is formed after calcination at 450 °C. The usual cha

TiO2 nanoparticles and Preyssler-type heteropoly acid modified nano-sized TiO2: A facile and efficient catalyst for the selective oxidation of sulfides to sulfones and sulfoxides

A new and efficient synthetic method has been developed for the selective conversion of sulfides into their corresponding sulfones and sulfoxides using H2O2 in the presence of neat or Preyssler-type heteropoly acid modified nano-sized TiO2 as catalyst, respectively. The reaction was performed at room temperature with quantitative yields. The catalyst is reusable without significant loss of activity for the next oxidation reaction.

Fullerene soot and a fullerene nanodispersion as recyclable heterogeneous off-the-shelf photocatalysts

Metal-free heterogeneous photocatalysis, which requires no prior catalyst immobilization or chemical modification and can operate in green solvents, represents a highly-sought after, yet currently still underdeveloped, synthetic method. In this report we present a comparative study which aims to evaluate the use of unmodified fullerene soot and a fullerene nanodispersion as non-soluble and quasi-soluble carbon-based photocatalysts, respectively, for sulfide oxidation and other transformations using oxygen as an oxidant in ethanol. A wide range of sulfoxides were successfully prepared with good yields and chemoselectivity using a very low catalyst loading. The fullerene soot photocatalyst is easily recovered and shows excellent stability of the catalytic properties. The reaction was shown to proceed via a singlet oxygen pathway and has a high selectivity for aliphatic sulfides, whereas the oxidation of thioanisoles can be accomplished using an amine mediated electron transfer mechanism. The applicability of the fullerene nanodispersion as a general purpose photocatalyst was demonstrated in radical cyclization, boronic acid oxidation and imine formation reactions.

Selective and mild oxidation of sulfides to sulfoxides by H2O2 using DBUH-Br3 as catalyst

DBUH-Br3 catalyzed selective conversion of sulfides to sulfoxides in the presence of H2O2 as oxidizing agent is described. The reaction was performed selectively at room temperature and relatively short reaction times.

Sodium sulfate-hydrogen peroxide-sodium chloride adduct: selective protocol for the oxidative bromination, iodination and temperature dependent oxidation of sulfides to sulfoxides and sulfones

The regioselective bromination and iodination of unprotected aromatic primary amines using enclathrated hydrogen peroxide as an oxidant under mild conditions has been developed, in which potassium bromide (KBr) and potassium iodide (KI) were used as brominating and iodinating agents, respectively. The adduct shows not only regioselectivity for para- or ortho-isomers but also a remarkable chemoselectivity for monobromination. Selective oxidation of sulfides to sulfoxides and sulfones has also been studied and good to excellent yields of the desired products were obtained. Acetic acid was found to be the solvent of choice for these reactions. This simple method represents an ecologically benign and alternative pathway for the oxidative halogenation of anilines and the oxidation of sulfides to sulfoxides and sulfones.

Nonanebis(peroxoic acid) mediated efficient and selective oxidation of sulfide

Two efficient and rapid protocols for the selective oxidation of sulfide in the presence of various oxidizable functionalities such as -CHO, -CH2-OH, alkene and tert amine were investigated, using nonanebis(peroxoic acid) as an oxidant. The acetonitrile based system offers selective oxidation to sulfoxide and sulfone, while the water based system gives selective sulfone formation with a high conversion and 90-100% selectivity. Recovery and recycling of the parent acid of up to 75-80% was achieved in the water based protocol.

4,4-Dibromo-3-methylpyrazol-5-one: New applications for selective monobromination of phenols and oxidation of sulfides to sulfoxides

Dibromopyrazolone 1, a stable, crystalline solid effects para selective monobromination of phenols and aniline substrates under mild conditions. Selective oxidation of sulfides to sulfoxides can also be accomplished by using 1 in high yields.

SYNTHESES OF 2-MERCAPTO- AND 2-ALKYLTHIO-1,3-PROPANEDIOL DERIVATIVES

Some synthetic routes to 2-alkylthio-1,3-propanediol derivatives, starting from commercially available compounds, are discussed.Treatment of diethyl 2-chloromalonate with thiolate anions followed by LiAlH4 reduction gave 9a,b,c in nearly 30percent overall