1085309-04-1

Basic information

• Product Name: (p-acetylamino)phenylacetaldehyde
• Synonyms: (p-acetylamino)phenylacetaldehyde
• CAS NO: 1085309-04-1
• Molecular Weight: 177.203
• Mol File: 1085309-04-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (p-acetylamino)phenylacetaldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: (p-acetylamino)phenylacetaldehyde(1085309-04-1)
• EPA Substance Registry System: (p-acetylamino)phenylacetaldehyde(1085309-04-1)

Safety Data

• Hazardous Substances Data: 1085309-04-1(Hazardous Substances Data)

Upstream product

• 83345-11-3 N-[4-(2-hydroxylethyl)phenyl]acetamide 

Downstream Products

• 1041643-82-6 C₁₃H₁₆N₂O₃S 
• 63891-85-0 N-(4-(3-methylbut-2-en-1-yl)phenyl)acetamide 
• 949512-92-9 2-[(1E)-(4-acetamidobenzyl)methylidene]toluenesulfonyl-hydrazone 
• 220647-56-3 N-{4-[2-(8-cyano-1,3a,4,9b-tetrahydro-3H-5-oxa-2-aza-cyclopenta[a]naphthalen-2-yl)-ethyl]-phenyl}-acetamide 
• 220647-56-3 N-{4-[2-(8-cyano-1,3a,4,9b-tetrahydro-3H-5-oxa-2-aza-cyclopenta[a]naphthalen-2-yl)-ethyl]-phenyl}-acetamide 
• 220647-56-3 S₃₃₁₃₈ 

Relevant articles and documents

Synthesis and antiproliferative activity of imidazole and imidazoline analogs for melanoma

We have previously reported substituted 2-aryl-thiazolidine-4-carboxylic acid amides as potent and selective antiproliferative agents for melanoma. To understand the importance of the thiazolidine ring and to reduce potential complications associated with the two chiral centers, we designed and synthesized sets of new analogs by modifying this ring. These new analogs were tested in two melanoma cell lines and fibroblast cells (negative controls). Compared with the older analogs containing the thiazolidine ring, these new analogs have lower potency in general, but some of these analogs still have very good selectivity. These structure-activity studies indicated that the thiazolidine ring is very critical for the activity for these series of compounds.