108541-05-5

Basic information

• Product Name: N-BENZOYL-ASPARTIC ACID-4-METHYL ESTER
• Synonyms: Asparticacid, N-benzoyl-, b-methyl ester, DL- (6CI)
• CAS NO: 108541-05-5
• Molecular Formula: C₁₂H₁₃NO₅
• Molecular Weight: 0
• Mol File: 108541-05-5.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: N-BENZOYL-ASPARTIC ACID-4-METHYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: N-BENZOYL-ASPARTIC ACID-4-METHYL ESTER(108541-05-5)
• EPA Substance Registry System: N-BENZOYL-ASPARTIC ACID-4-METHYL ESTER(108541-05-5)

Safety Data

• Hazardous Substances Data: 108541-05-5(Hazardous Substances Data)

Upstream product

• 98-88-4 benzoyl chloride 
• 1835-52-5 L-Aspartic acid beta-methyl ester hydrochloride 

Downstream Products

• 100373-13-5 methyl 3-benzamido-4-oxovalerate 
• 60272-64-2 2-phenyl-4-methoxycarbonylmethyl-5-oxo-4,5-dihydro-1,3-oxazole 
• 101793-94-6 N²-benzoyl-N¹-phenyl-DL-isoasparagine methyl ester 
• 134308-22-8 4-benzoylamino-4-carboxy-γ-butyrolactone 
• 97640-33-0 4-benzoylamino-4-carboxy-γ-butyrolactone 
• 97640-32-9 4-benzoylamino-4-carboxy-γ-butyrolactone 
• 97640-30-7 5-benzoylamino-5-methoxycarbonylmethylene-4-oxo-1,3-dioxane 
• 97640-31-8 N-benzoyl-α-hydroxymethylaspartic acid β-methyl ester 

Relevant articles and documents

Dynamic Kinetic Resolution of Azlactones by a Chiral N, N-Dimethyl-4-aminopyridine Derivative Containing a 1,1′-Binaphthyl Unit: Importance of Amide Groups

A dynamic kinetic resolution (DKR) of azlactones in the presence of benzoic acid and a binaphthyl-based N,N-4-dimethylaminopyridine (DMAP) derivative 1i having two amide groups at the 3,3′-positions of a binaphthyl unit is developed. The reaction proceeded smoothly with a wide range of azlactones to provide α-amino acid derivatives with good to high enantiomeric ratios (er's). A multigram-scale reaction (2.5 g) for the DKR of azlactone 2d was also demonstrated, and the resulting product was converted to unnatural α-amino acid 6d′.