1835-52-5

Basic information

• Product Name: H-DL-ASP(OME)-OH HCL
• Synonyms: DL-ASPARTIC ACID 4-METHYL ESTER HYDROCHLORIDE;DL-ASPARTIC ACID BETA-METHYL ESTER HYDROCHLORIDE;DL-ASPARTIC ACID(OME)-OH HCL;IFLAB-BB F2108-0160;H-DL-ASP(OME)-OH HCL;4-methyl hydrogen DL-aspartate hydrochloride;DL-ASPARTIC ACID B-METHYL ESTER &;DL-Asparticacid4-methylesterHCl
• CAS NO: 1835-52-5
• Molecular Formula: C₅H₉NO₄*ClH
• Molecular Weight: 183.59
• EINECS: 217-399-4
• Mol File: 1835-52-5.mol
• Article Data: 3

Chemical Properties

• Melting Point: 196-200 °C
• Boiling Point: 329 °C at 760 mmHg
• Flash Point: 152.8 °C
• Appearance: /
• Vapor Pressure: 8E-05mmHg at 25°C
• Storage Temp.: −20°C
• CAS DataBase Reference: H-DL-ASP(OME)-OH HCL(CAS DataBase Reference)
• NIST Chemistry Reference: H-DL-ASP(OME)-OH HCL(1835-52-5)
• EPA Substance Registry System: H-DL-ASP(OME)-OH HCL(1835-52-5)

Safety Data

• Safety Statements: 22-24/25
• WGK Germany: 3
• Hazardous Substances Data: 1835-52-5(Hazardous Substances Data)

Usage

Chemical Properties

White powder

InChI:InChI=1/C5H9NO4.ClH/c1-5(9,10)2-3(6)4(7)8;/h6,9-10H,2H2,1H3,(H,7,8);1H/b6-3-;

Upstream product

• 617-45-8 aspartic Acid 
• 67-56-1 methanol 

Downstream Products

• 108541-05-5 N-benzoylaspartic acid β-methyl ester 
• 4276-08-8 β-methyl N-benzyloxycarbonyl-DL-aspartate 
• 1093678-97-7 2-(3-nitrobenzamido)-4-methoxy-4-oxobutanoic acid 
• 1093678-92-2 2-(4-tert-butylbenzamido)-4-methoxy-4-oxobutanoic acid 
• 1093678-96-6 2-(3-fluorobenzamido)-4-methoxy-4-oxobutanoic acid 
• 851181-28-7 2-(4-fluorobenzamido)-4-methoxy-4-oxobutanoic acid 

Relevant articles and documents

Dynamic Kinetic Resolution of Azlactones by a Chiral N, N-Dimethyl-4-aminopyridine Derivative Containing a 1,1′-Binaphthyl Unit: Importance of Amide Groups

A dynamic kinetic resolution (DKR) of azlactones in the presence of benzoic acid and a binaphthyl-based N,N-4-dimethylaminopyridine (DMAP) derivative 1i having two amide groups at the 3,3′-positions of a binaphthyl unit is developed. The reaction proceeded smoothly with a wide range of azlactones to provide α-amino acid derivatives with good to high enantiomeric ratios (er's). A multigram-scale reaction (2.5 g) for the DKR of azlactone 2d was also demonstrated, and the resulting product was converted to unnatural α-amino acid 6d′.

Efficient preparation of D-aspartic acid β-methyl ester as an aspoxicillin material by optical resolution, epimerization, and asymmetric transformation

-